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Baltimore Orioles vs Detroit Tigers Prediction 4/25/25 MLB Picks

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Detroit Tigers (15-10) vs Baltimore Orioles (10-14)

Game Info: Friday, April 25, 2025 at 6:40 pm (Comerica Park)

The Line: Betting Odds: Detroit Tigers -130 / Baltimore Orioles +110 — Over/Under: 8.5

(Get latest betting odds)

The Baltimore Orioles and the Detroit Tigers meet Monday in MLB action from Comerica Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Baltimore Orioles vs. Detroit Tigers prediction.

Starting Pitching Matchup

The Baltimore Orioles will send out Brandon Young for the start here and Young is 0-0 with a 6.75 ERA and 3 strikeouts this season. This will be Young’s first career start against the Tigers. Casey Mize will get the start for the Tigers here and is 3-1 with a 2.22 ERA and 18 strikeouts this season. In his career, Mize is 1-0 with a 2.38 ERA and 6 strikeouts against Baltimore.

Baltimore Orioles Recap

The Baltimore Orioles come into this game looking to build on their 2-1 win over the Washington Nationals in Thursday’s series finale to improve to 10-14 on the year. After this series, the Orioles will head home for a divisional series against the Yankees.

Orioles Snap Three-Game Losing Skid & Salvage Win Vs. Nationals.

Cedric Mullins has a team-high 23 hits so far this season as well as team-highs of 5 doubles, 6 home runs and 20 RBIs with 5 stolen bases and a .295 batting average while Adley Rutschman has 18 hits with a pair of doubles, 4 homers and 8 RBIs. Ryan Mountcasle has 17 hits with 4 doubles and Tyler O’Neill has 14 hits with 3 doubles, a triple and 2 homers with 10 RBIs. Jordan Westburg’s added 4 home runs and Gunnar Henderson has a team-high 23 strikeouts as well this season.

Why the Baltimore Orioles will win

Baltimore Orioles Player Prop Facts

Detroit Tigers Recap

The Detroit Tigers come into this series looking to build on their 6-0 win over the San Diego Padres from Wednesday’s series finale to improve to 15-10 on the year. After this series, the Tigers will head on the road for a series against the Houston Astros.

Tigers Win Second Straight Series

Spencer Torkelson leads the Tigers with 24 hits along with a .264 batting average including a team-high 7 home runs, 7 doubles and 21 RBIs. Kerry Carpenter also has 5 home runs and 11 RBIs while Riley Greene has 22 hits with 4 doubles, 3 home runs and 10 RBIs but also has a team-high 34 strikeouts as well this season. Trey Sweeney also has 15 hits with 2 doubles, a triple and a home run and 8 RBIs. Dillon Dingler has 3 home runs and 11 RBIs and Zack McKinstry’s added 3 triples, a home run and 12 RBIs of his own along with 23 hits as well this season.

Why the Detroit Tigers will win

Detroit Tigers Player Prop Facts

Total Runs Facts

Baltimore Orioles vs. Detroit Tigers Prediction

I’m on the Tigers here. I just didn’t love what I saw from Young in his major league debut, and the Tigers are rolling offensively right now, and have been crushing teams at home this season. The Orioles I think were lucky to salvage a win from their series with Washington to start the week, and I don’t think they’ll be as fortunate here with how the Tigers are rolling along and how well Mize has pitched to this point. Give me Detroit at home in this one.

Chris Ruffolo's Pick: Detroit Tigers -130

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