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Baltimore Orioles vs Boston Red Sox Prediction 5/25/25 MLB Picks

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Boston Red Sox (27-27) vs Baltimore Orioles (17-34)

Game Info: Sunday, May 25, 2025 at 1:35 pm (Fenway Park)

The Line: Betting Odds: Boston Red Sox -135 / Baltimore Orioles +114 — Over/Under: 9.5

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The Baltimore Orioles and Boston Red Sox meet Sunday in MLB action at Fenway Park. Here’s a Baltimore Orioles vs Boston Red Sox Prediction. This article will include a Baltimore Orioles vs Boston Red Sox Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 17-34 on the year and play the Cardinals, White Sox, and Mariners next. The Baltimore Orioles are batting .235 on the season, have a .303 OBP, and a .385 slugging percentage. The Baltimore Orioles pitching staff has a 5.61 ERA and a 1.49 WHIP. Gunnar Henderson leads the Baltimore Orioles with 47 hits and 14 RBI, while Ryan O’Hearn and Jackson Holliday have combined for 90 hits and 39 RBI. 

Dean Kremer gets the ball for the Baltimore Orioles, and he is 3-5 with a 5.50 ERA and 40 strikeouts this season. Kremer is 2-4 with a 5.64 ERA and 40 strikeouts in his career against the Boston Red Sox.

Boston Red Sox Betting Preview

The Boston Red Sox are 27-26 on the year and play the Brewers, Braves, and Angels next. The Boston Red Sox are batting .254 on the season, have a .326 OBP, and a .427 slugging percentage. The Boston Red Sox pitching staff has a 4.02 ERA and a 1.35 WHIP. Jarren Duran leads the Boston Red Sox with 61 hits and 33 RBI, while Rafael Devers and Alex Bregman have combined for 119 hits and 83 RBI.

Walker Buehler gets the ball for the Boston Red Sox, and he is 4-1 with a 4.00 ERA and 33 strikeouts this season. Buehler is 1-0 with a 1.54 ERA and 15 strikeouts in his career against the Baltimore Orioles.

Why the Boston Red Sox will win

Why the Baltimore Orioles will win

Boston Red Sox Player Prop Facts

Baltimore Orioles Player Prop Facts

  • Dylan Carlson has recorded an RBI in four of his last five appearances against the Red Sox.
  • Dean Kremer has recorded six or more strikeouts in five of his last six appearances with the Orioles as road underdogs against AL East opponents.
  • Ryan O’Hearn has recorded at least one Single in each of the Orioles’ last six games as road underdogs against AL East opponents.
  • Ramon Urias has recorded at least one hit in each of his last seven road appearances.
  • Jordan Westburg has hit a home run in two of his last three road appearances against the Red Sox.
  • Ramon Laureano has recorded at least one Double in three of his last four appearances with the Orioles as underdogs against AL opponents.
  • Jorge Mateo has scored at least one run in eight of his last nine appearances with the Orioles as road underdogs against the Red Sox.

Baltimore Orioles vs Boston Red Sox Prediction

The Orioles are a team I’ll continue to fade, and despite them splitting the doubleheader yesterday, they haven’t won two straight games since April 30-May 2. I want nothing to do with the Orioles, and it doesn’t help with Kremer on the mound, a pitcher with a 5.50 ERA and 1.38 WHIP. In 37.2 road innings, Kremer has a 6.93 ERA and a .308 allowed batting average. Buehler has been hit or miss, but he’s allowed seven hits and three runs in his last 8.1 innings. We know what Buehler is capable of when he’s right, a two-time all-star and two-time World Series winner. I’ll gladly take the soft price with the Red Sox at home.

Randy Chambers's Pick: Boston Red Sox -135

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