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Baltimore Orioles vs Arizona Diamondbacks Prediction 4/9/25 MLB Picks

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Joe Rondone/The Republic / USA TODAY NETWORK via Imagn Images

Arizona Diamondbacks (6-6) vs Baltimore Orioles (5-7)

Game Info: Wednesday, April 9, 2025 at 3:40 pm (Chase Field)

The Line: Betting Odds: Arizona Diamondbacks -125 / Baltimore Orioles +105 — Over/Under: 9

(Get latest betting odds)

The Baltimore Orioles and Arizona Diamondbacks meet on Wednesday in MLB action at Chase Field. Here’s a Baltimore Orioles vs Arizona Diamondbacks Prediction. This article will include a Baltimore Orioles vs Arizona Diamondbacks Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 5-7 on the year and play the Blue Jays, Guardians, and Reds next. The Baltimore Orioles are batting .250 on the season, have a .319 OBP, and a .396 slugging percentage. The Baltimore Orioles pitching staff has a 4.37 ERA and a 1.34 WHIP. Cedric Mullins leads the Baltimore Orioles with 12 hits and 14 RBI, while Ryan Mountcastle and Adley Rutschman have combined for 23 hits and 7 RBI. 

Dean Kremer gets the ball for the Baltimore Orioles, and he is 1-1 with a 6.52 ERA and 7 strikeouts this season. This will be Kremer’s second career game against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 6-6 on the year and play the Brewers, Marlins, and Cubs next. The Arizona Diamondbacks are batting .249 on the season, have a .340 OBP, and a .428 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.80 ERA and a 1.20 WHIP. Corbin Carroll leads the Arizona Diamondbacks with 14 hits and 7 RBI, while Josh Naylor and Geraldo Perdomo have combined for 25 hits and 18 RBI.

Brandon Pfaadt gets the ball for the Arizona Diamondbacks, and he is 1-1 with a 5.25 ERA and 9 strikeouts this season. This will be Pfaadt’s second career game against the Baltimore Orioles.

Why the Arizona Diamondbacks will win

Why the Baltimore Orioles will win

Matchup/League Facts

  • The Diamondbacks rank 3rd in the league for strikeouts this season (112).
  • The Diamondbacks rank T4th in the league for strikeouts against this season (77).
  • The Orioles rank T8th in the league for runs scored this season (55).
  • The Orioles rank 8th in the league for hits this season (99).

Baltimore Orioles vs Arizona Diamondbacks Prediction

The Baltimore Orioles continue to have issues finishing games, and they’ve underachieved through their first 12 games. Kremer has been up and down these last couple of seasons, and he’s been hit hard through 9.2 innings this season. Pfaadt has had his issues as well, and he has an ERA over five through 52 career MLB starts. The difference in this spot is the Diamondbacks have the more consistent offense, and it’s easier to have confidence Arizona can work its way around a bad inning or two from its pitching staff. The line is cheap. Give me the Diamondbacks to win the series against the Orioles.

Randy Chambers's Pick: Arizona Diamondbacks -125

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