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Athletics vs Boston Red Sox Prediction 9/18/2025 Today’s MLB Picks

Sep 17, 2025; Boston, Massachusetts, USA; Boston Red Sox third baseman Nate Eaton (40) slides across home plate against Athletics catcher Shea Langeliers (23) to score the winning run off an RBI by first baseman Nick Sogard (20) (not pictured) during the tenth inning at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images

Sep 17, 2025; Boston, Massachusetts, USA; Boston Red Sox third baseman Nate Eaton (40) slides across home plate against Athletics catcher Shea Langeliers (23) to score the winning run off an RBI by first baseman Nick Sogard (20) (not pictured) during the tenth inning at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images

Oakland (71-81) vs Boston (83-69)

September 18, 2025 at 01:35 PM EDT

The Line: Betting Odds: Boston -1.5 — Over/Under: +9

(Get latest betting odds)

The Athletics and Boston Red Sox meet Thursday in MLB action at Fenway Park. Here’s a Athletics vs Boston Red Sox Prediction. This article will include a Athletics vs Boston Red Sox Pick.

Athletics Betting Preview

The Athletics are 71-81 on the year and play the Pirates, Astros, and Royals next. The Athletics are batting .255 on the season, have a .321 OBP, and a .436 slugging percentage. The Athletics pitching staff has a 4.73 ERA and a 1.36 WHIP. Brent Rooker leads the Athletics with 159 hits and 85 RBI, while Tyler Soderstrom and Jacob Wilson have combined for 293 hits and 148 RBI.

J.T. Ginn gets the ball for the Athletics, and he is 3-6 with a 4.69 ERA and 92 strikeouts this season. This will be Ginn’s first career game against the Boston Red Sox.

Boston Red Sox Betting Preview

The Boston Red Sox are 83-69 on the year and play the Rays, Blue Jays, and Tigers next. The Boston Red Sox are batting .254 on the season, have a .324 OBP, and a .423 slugging percentage. The Boston Red Sox pitching staff has a 3.73 ERA and a 1.29 WHIP. Jarren Duran leads the Boston Red Sox with 152 hits and 80 RBI while Trevor Story and Ceddanne Rafaela have combined for 274 hits and 152 RBI.

Brayan Bello gets the ball for the Boston Red Sox, and he is 11-7 with a 3.25 ERA and 118 strikeouts this season. Bello is 1-1 with a 9.42 ERA and 20 strikeouts in his career against the Athletics.

Athletics @ Boston Red Sox Betting Trends: September 18, 2025

  • Probable Starting Pitcher: Brayan Bello      Record this season: 11-7      ERA: 3.25
  • Home Record: 8-4
  • Last 5 against Athletics: 1-1

Why the Boston Red Sox will win

  • The Red Sox have won 11 of their last 12 day games against AL West opponents following a home win.
  • The Athletics have lost four of their last five road games after playing the previous day.
  • The Red Sox have covered the run line in four of their last five home games after going to extra innings.
  • The Athletics have trailed after 3 innings in five of their last six games against American League opponents.
  • The Athletics have trailed after 5 innings in three of their last four day games against American League opponents.
  • Probable Starting Pitcher: J.T. Ginn      Record this season: 3-6      ERA: 4.69
  • Road Record: 2-2
  • Last 5 against Red Sox: –

Why the Athletics will win

  • The Athletics have won each of their last five games as road underdogs against American League opponents following a loss.
  • The Red Sox have lost three of their last four games as favorites following a win.
  • The Athletics have covered the run line in each of their last eight road games against AL East opponents.
  • The Red Sox have failed to cover the run line each of their last six games at Fenway Park against American League opponents that held a losing record.
  • The Athletics have led after 5 innings in four of their last five games as road underdogs.

Total Runs Facts

  • Five of the Athletics’ last six games as underdogs against the Red Sox have gone UNDER the total runs line.
  • Five of the Red Sox’s last six games against AL West opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Red Sox’s last eight games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last four day games against American League opponents.

Boston Red Sox Player Prop Facts

  • Triston Casas has hit a home run in three of his last four appearances with the Red Sox as home favorites against AL West opponents.
  • Connor Wong has recorded at least one hit in each of his last eight appearances in day games against AL teams that held a losing record.

Athletics Player Prop Facts

  • Nick Kurtz has hit a home run in each of the Athletics’ last two day games.
  • Shea Langeliers has recorded at least one hit in each of his last six road appearances.
  • Jacob Wilson is one of only eight players to hit over .300 and have 45+ RBIs this season.

Matchup/League Facts

  • The Red Sox rank 4th in the league for ERA this season (3.73).
  • The Red Sox rank T4th in the league for home runs allowed this season (155).
  • The Athletics rank 28th in the league for walks allowed this season (531).
  • The Athletics rank T28th in the league for home runs allowed this season (210).

Athletics vs Boston Red Sox Prediction

The Athletics are doing a fine job of playing spoiler, and Ginn has allowed just 7 hits and 1 run in his last 9.1 innings. Ginn is also one of many Athletics who has been better on the road than at home this season. Still, I’m rolling with the Red Sox. The Red Sox have things to play for still, which is an advantage entering the last week. Bello has had issues in September, but he has a 3.25 ERA and 1.22 WHIP on the season, and the Red Sox have won 7 of his last 9 starts. The Red Sox simply can’t afford to blow games like this if they’re seriously trying to lock up a playoff spot. Give me the home team.

Randy Chambers's Pick: Boston Red Sox

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