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Astros vs Rays Prediction 9/12/2026 Today’s MLB Picks

Aug 25, 2025; Cleveland, Ohio, USA; Tampa Bay Rays third baseman Junior Caminero (13) celebrates his two-run home run in the fifth inning against the Cleveland Guardians at Progressive Field. Mandatory Credit: David Richard-Imagn Images

Aug 25, 2025; Cleveland, Ohio, USA; Tampa Bay Rays third baseman Junior Caminero (13) celebrates his two-run home run in the fifth inning against the Cleveland Guardians at Progressive Field. Mandatory Credit: David Richard-Imagn Images

MATCHUP Houston Astros Tampa Bay Rays
Team Records 75-73 88-59
Spread +1.5 -174 -1.5 143
Moneyline +123 -149
Total Over 8 (-110) Under 8 (-110)
Where Tropicana Field, St. Petersburg, Florida
When Saturday, September 12, 2026
Time 06:10 PM EDT
TV MLB.TV
In this article we will formulate an Astros vs Rays prediction for this MLB game on Saturday, September 12th at Tropicana Field in St. Petersburg, Florida. Let’s take a look at the prediction for this MLB matchup. 

Houston Astros Betting Preview

The Houston Astros are 75-73 this season after they lost game one by a score of 1-3 on Friday. Houston led 1-0 in the fourth inning, but they failed to score over the last five innings for the loss. The Astros recorded nine hits in the game and they were led by Diaz, who went 2-3 with one RBI. Ullola opened the game, while Abreu allowed two earned runs for the loss. Prior to this series, Houston won two out of three against the Phillies, but lost two out of three against the Diamondbacks before that. 

This season, Houston has a 4.51 ERA with a 1.34 WHIP and a .238 opponent batting average, while they have scored 663 runs with a .241 batting average and a .315 on base percentage. Yordan Alvarez has led the Astros with 38 home runs and 96 RBIs, while Christian Walker has added 25 home runs and 80 RBIs. The projected starting pitcher for Houston is Peter Lambert, who is 8-8 with a 3.67 ERA and a 1.23 WHIP over 139.2 innings pitched this season. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 88-59 this year after they won game one by a score of 3-1 last night. Tampa Bay tied the game in the fifth inning and they scored two runs in the ninth for the win. The Rays recorded four hits in the game and they were led by Caminero, who went 1-4 with one home run and two RBIs. Rasmussen allowed eight hits and one earned run over 7.0 innings, while Baker picked up the win in relief. Prior to this series, Tampa Bay won two out of three against the Braves and split four games with the Rangers. 

This season, Tampa Bay has a 3.79 ERA with a 1.15 WHIP and a .231 opponent batting average, while they have scored 665 runs with a .260 batting average and a .328 on base percentage. Jonathan Aranda has led the Rays with 19 home runs and 86 RBIs, while Junior Caminero has added 40 home runs and 95 RBIs. The projected starting pitcher for Tampa Bay is Ian Seymour, who is 9-6 with a 4.33 ERA and a 1.16 WHIP over 116.1 innings pitched this year. 

Why the Tampa Bay Rays will win

Why the Houston Astros will win

Total Runs Facts

Tampa Bay Rays Player Prop Facts

Houston Astros Player Prop Facts

Astros vs Rays Prediction 

Tampa Bay was able to start this series with a win on Friday and they have won three of their last four games. The Rays are 48-25 at home this year, while the Astros are 38-35 on the road. Houston has alternated wins and losses over their last five games and they have scored two runs or fewer in three of those five. The Astros are starting Lambert, who has allowed two earned runs or fewer in three of his last five outings, while Seymour has allowed three earned runs in five straight starts. Take the over in this one.

David Racey's Pick: Over 8

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