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Arizona Diamondbacks vs St. Louis Cardinals Prediction 6/24/2026 Today’s MLB Picks

Jun 23, 2026; St. Louis, Missouri, USA; Arizona Diamondbacks left fielder Tommy Troy (9) leaps at the wall but is unable to catch a double hit by St. Louis Cardinals center fielder Lars Nootbaar (not pictured) during the ninth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

Jun 23, 2026; St. Louis, Missouri, USA; Arizona Diamondbacks left fielder Tommy Troy (9) leaps at the wall but is unable to catch a double hit by St. Louis Cardinals center fielder Lars Nootbaar (not pictured) during the ninth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

MATCHUP Arizona Diamondbacks St. Louis Cardinals
Team Records 40-39 42-35
Spread -1.5 161 +1.5 -197
Moneyline -102 -118
Total Over 9 (-108) Under 9 (-112)
Where Busch Stadium, St. Louis, Missouri
When Wednesday, June 24, 2026
Time 07:45 PM EDT
TV MLB.TV
The Arizona Diamondbacks and St. Louis Cardinals meet Wednesday in MLB action at Busch Stadium. Here’s an Arizona Diamondbacks vs St. Louis Cardinals Prediction. This article will include an Arizona Diamondbacks vs St. Louis Cardinals Pick.

Arizona Diamondbacks Betting Preview


The Arizona Diamondbacks are 40-39 on the year and play the Giants and Rays next. The Arizona Diamondbacks are batting. 238 on the season, have a .309 OBP, and have a .383 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.29 ERA and a 1.30 WHIP. Corbin Carroll leads the Arizona Diamondbacks with 79 hits and 42 RBI, while Ketel Marte and Ildemaro Vargas have combined for 142 hits and 88 RBI.

Mitch Bratt will make his major league debut when he takes the mound tonight. Bratt was 23-19 with a 3.22 ERA and 492 strikeouts in his minor league career. This season in AAA, Bratt is 1-1 with a 2.84 ERA and 42 strikeouts. Bratt is considered the 14th best prospect in the Diamondbacks farm system.

St. Louis Cardinals Betting Preview


The St. Louis Cardinals are 42-35 on the year and play the Braves and Marlins next. The St. Louis Cardinals are batting .249 on the season, with a .328 OBP and a .399 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.25 ERA and a 1.34 WHIP. Jordan Walker leads the St. Louis Cardinals with 87 hits and 58 RBI, while Alec Burleson and JJ Wetherholt have combined for 162 hits and 91 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 3-4 with a 5.23 ERA and 67 strikeouts this season. This will be Liberatore’s second career game against the Arizona Diamondbacks.

Why the St. Louis Cardinals will win

Why the Arizona Diamondbacks will win

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Matchup/League Facts

Arizona Diamondbacks vs St. Louis Cardinals Prediction


I’m not thrilled to get behind Liberatore and his 5.25 ERA and 1.56 WHIP through 72.1 innings. However, the price is low, and those who have followed me over the years know I rarely back pitchers making their MLB debut. I like sample sizes with my pitchers, and we have no idea what to expect from Bratt. Also, Bratt has had issues with velocity and movement throughout his time in the minors, which will work against him in the big leagues. I’m siding with the Cardinals on Wednesday night.

Randy Chambers's Pick: St. Louis Cardinals

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