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Arizona Diamondbacks vs Pittsburgh Pirates Prediction 7/27/2026 Today’s MLB Picks

Apr 25, 2026; Milwaukee, Wisconsin, USA;  Pittsburgh Pirates pitcher Mitch Keller (23) throws a pitch during the second inning against the Milwaukee Brewers at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

Apr 25, 2026; Milwaukee, Wisconsin, USA; Pittsburgh Pirates pitcher Mitch Keller (23) throws a pitch during the second inning against the Milwaukee Brewers at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images

MATCHUP Arizona Diamondbacks Pittsburgh Pirates
Team Records 55-51 54-52
Spread +1.5 -194 -1.5 159
Moneyline +102 -123
Total Over 9 (-105) Under 9 (-115)
Where PNC Park, Pittsburgh, Pennsylvania
When Monday, July 27, 2026
Time 06:40 PM EDT
TV MLB.TV
In this article, we will formulate a Diamondbacks vs Pirates Prediction for this MLB matchup on Monday, July 27th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Preview


The Pittsburgh Pirates have a 54-52 record this season and are sitting in the 3rd place of the NL Central. They have a 28-26 home record and are coming off an 8-7 home win against the Cubs. They will face the Reds and the Brewers next.

The Pittsburgh Pirates have a .260 batting average this season, .338 OBP and .422 Slugging percentage. Pittsburgh’s pitching staff has a 4.32 ERA and 1.32 WHIP. Nick Gonzales is the team’s best hitter with a .313 batting average. Ryan O’Hearn leads the team in RBI with 68, while Brandon Lowe adds a team-high 21 home runs.

Mitch Keller (R) is the projected starting pitcher for the Pittsburgh Pirates, and he has a 6-7 record, 4.90 ERA and 1.31 WHIP.

Arizona Diamondbacks Preview


The Arizona Diamondbacks have a 55-51 record this season and are sitting in the 2nd place of the NL West. They have a 24-29 away record and are coming off a 7-10 road loss against the Nationals. They will face the Guardians and the Padres next.

The Arizona Diamondbacks have a .242 batting average this season, .314 OBP and .395 Slugging percentage. Arizona’s pitching staff has a 4.27 ERA and 1.30 WHIP. Ildemaro Vargas is the team’s best hitter with a .272 batting average. Ketel Marte leads the team in RBI with 61, adding a team-high 19 home runs.

Merrill Kelly (R) is the projected starting pitcher for the Arizona Diamondbacks, and he has a 8-8 record, 5.12 ERA and 1.48 WHIP.

Arizona Diamondbacks @ Pittsburgh Pirates Betting Trends: July 27, 2026


Why the Pittsburgh Pirates will win

Why the Arizona Diamondbacks will win

Total Runs Facts

Pittsburgh Pirates Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Matchup/League Facts

Diamondbacks vs Pirates Prediction


The Pirates are 4-1 in their last 5 meetings against the Diamondbacks and have won their last two meetings in Pittsburgh.

In this Diamondbacks vs Pirates Prediction, the Pirates are coming as -120 home favorites. I don’t trust either pitcher in this matchup, as they both have a combined 10.02 ERA and both offenses have been red-hot lately, averaging 11.5 runs per game combined in their last 10 games. On top of that, both bullpens have been bottom-8 in the league after the break and they are 7-2 to the over in their last 9 games combined, so I am expecting a high-scoring affair today. Take the over 9 runs.

Nikos Lagouretos's Pick: Over 9

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