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Arizona Diamondbacks vs Chicago Cubs Prediction 5/3/2026 Today’s MLB Picks

Mar 26, 2026; Chicago, Illinois, USA;  Chicago Cubs pitcher Matthew Boyd (16) waits to pitch first inning against the Washington Nationals at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

Mar 26, 2026; Chicago, Illinois, USA; Chicago Cubs pitcher Matthew Boyd (16) waits to pitch first inning against the Washington Nationals at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Arizona Diamondbacks Chicago Cubs
Team Records 16-16 21-12
Spread +1.5 -136 -1.5 113
Moneyline +129 -156
Total Over 11.5 (-105) Under 11.5 (-115)
Where Wrigley Field, Chicago, Illinois
When Sunday, May 3, 2026
Time 02:20 PM EDT
TV MLB.TV

In this article, we will formulate a Diamondbacks vs Cubs Prediction for this MLB matchup on Sunday, May 3rd in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 21-12 record this season and are sitting in the first place of the NL Central. They have a 13-5 home record and are coming off a 2-0 win at home against the Diamondbacks. Their previous three games were a 6-5 win at home against the Diamondbacks, a 5-4 win and an 8-3 win on the road against the Padres.

The Cubs have a .258 batting average this season, .350 OBP and .425 Slugging percentage. Chicago’s pitching staff has a 3.89 ERA and 1.18 WHIP. Nico Hoerner is the team’s best hitter with a .297 batting average, also leading the team in RBI with 26. Ian Happ adds a team‑high 8 home runs.

Matthew Boyd (L) is the projected starting pitcher for the Cubs, and he has a 1-1 record, 7.00 ERA and 1.44 WHIP.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 16-16 record this season and are sitting in the third place of the NL West. They have a 7-10 away record and are coming off a 0-2 loss on the road against the Cubs. Their previous three games were a 5-6 loss on the road against the Cubs, a 1-13 loss and a 6-2 win on the road against the Brewers.

The Diamondbacks have a .248 batting average this season, .304 OBP and .410 Slugging percentage. Arizona’s pitching staff has a 4.96 ERA and 1.39 WHIP. Ildemaro Vargas is the team’s best hitter with a .388 batting average, also leading the team in RBI with 21 and adding a team‑high 6 home runs.

Merrill Kelly (R) is the projected starting pitcher for the Diamondbacks, and he has a 1-2 record, 9.20 ERA and 2.25 WHIP.

Arizona Diamondbacks @ the Chicago Cubs Betting Trends: May 3, 2026

Why the Chicago Cubs will win

Why the Arizona Diamondbacks will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Matchup/League Facts

Diamondbacks vs Cubs Prediction

The Cubs are 4-1 in their last 5 meetings against the Diamondbacks and are 5-1 in their last 6 meetings in Chicago.

In this Diamondbacks vs Cubs Prediction, the Cubs are coming as -160 home favorites. Both starting pitchers have been atrocious so far with a combined 16.20 ERA and you got winds blowing out in Wrigley Field by more than 20 miles per hour, so this will be a high-scoring games, as expected by the books who set the total at 12 runs. Kelly has 13 earned runs in his last two starts and Boyd gave up 5 runs in his last start. Arizona is the best team against lefties this season and ranks 25th in bullpen ERA while the Cubs have the second-best offense in baseball. I will gladly go over that big number today, so take the over 12.

Nikos Lagouretos's Pick: Over 12

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