Angels vs Twins Prediction 4/25/25 MLB Picks

In this article we will formulate an Angels vs Twins prediction for this MLB game on Friday, April 25th at Target Field in Minneapolis, Minnesota. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Angels Betting Preview

The Los Angeles Angels are 12-12 this year after they lost two out of three against Pittsburgh by scores of 3-9, 0-3, and 4-3. In their game three win, Los Angeles trailed 3-0 after the second inning, but they scored the last four runs in the game to escape with the win. The Angels recorded six hits in the game and they were led by O’Hoppe, who went 1-4 with one home run and two RBIs in the win. LA started Anderson, who allowed six hits and three earned runs over 6.0 innings, while Jansen locked down the save in the ninth. 

Prior to that series, the Angels won two out of three against the Giants, but did lose all three against the Rangers before that. Los Angeles has split their last six games and they are currently fourth in the AL West standings. The Los Angeles pitching staff has a 4.44 ERA with a 1.42 WHIP and a .258 opponent batting average, while the offense has scored 95 runs with a .215 batting average and a .272 on base percentage this season. Mike Trout has led LA with eight home runs and 16 RBIs, while Logan O’Hoppe has added six home runs and 11 RBIs this year. The projected starting pitcher for Los Angeles is Kyle Hendricks, who is 0-2 with a 4.50 ERA and a 1.20 WHIP over 20.0 innings pitched this year. 

Minnesota Twins Betting Preview

The Minnesota Twins are 9-16 this season after they won two out of three against the White Sox by scores of 4-2, 6-3, and 0-3. In the game three loss, the Twins allowed one run in the second inning, one in the fourth, and one in the sixth in the rain shortened loss. Minnesota recorded six hits in the game and they were led by Lee and Vazquez, who both had two hits in the loss. Minnesota started Paddack, who allowed five hits and two earned runs over 5.0 innings for the loss, while Alcala allowed one earned run and three hits in 2.0 innings of relief. 

Prior to that series, the Twins lost all three against the Braves, but did win two out of three against the Mets before that. Minnesota has lost four of their last six games and they are currently fourth in the AL Central standings. The Minnesota pitching staff has a 3.89 ERA with a 1.26 WHIP and a .244 opponent batting average, while their offense has scored 85 runs with a .216 batting average and a .293 on base percentage this season. Byron Buxton has led Minnesota with five home runs and 12 RBIs, while Harrison Bader has added three home runs and 12 RBIs this year. The projected starting pitcher for Minnesota is Pablo Lopez, who is 1-1 with a 1.62 ERA and a 1.02 WHIP over 16.2 innings pitched this season. 

Why the Twins will beat the Angels 

• The home team has won seven of the Twins’ last eight games.
• The Angels have lost seven of their last eight night games following a home win.
• The Angels have failed to cover the run line in each of their last six road games against AL Central opponents following a win.
• The Twins have covered the run line in each of their last five home games against AL West opponents following a home loss.
• The Twins have led after 3 innings in four of their last five home night games.
• The Angels have trailed after 5 innings in three of their last four road games.

Total Runs Facts

• Each of the Angels’ last five night games as underdogs have gone UNDER the total runs line.
• Six of the Twins’ last seven games as home favorites have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last nine Friday night games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last four games against AL Central opponents.

Minnesota Twins Player Prop Facts

• Trevor Larnach has hit a home run in each of the Twins’ last two night games.
• Pablo Lopez has recorded a win in four of his last five appearances at Target Field.
• Trevor Larnach has recorded at least one Single in each of his last four appearances against the Angels.
• Pablo Lopez has recorded seven or more strikeouts in each of his three previous appearances with the Twins as favorites against the Angels.
• Byron Buxton has scored at least one run in each of his last seven appearances against AL West opponents at Target Field.
• Jonah Bride has recorded at least one RBI in four of his last five appearances against AL opponents.
• Willi Castro has recorded a hit in each of his eight previous home appearances against the Angels.

Los Angeles Angels Player Prop Facts

• Taylor Ward has hit at least one home run in four of the Angels’ last five road games against opponents that held a losing record.
• Mike Trout has recorded at least one RBI in each of his last four appearances against the Twins at Target Field.
• Luis Rengifo has recorded at least one hit in each of his last 13 appearances against AL Central opponents that held a losing record.
• Kyle Hendricks has recorded three or more strikeouts in each of his last eight road appearances against AL Central opponents.
• Yoan Moncada has recorded a Double in each of his last three road appearances against the Twins.
• Tim Anderson has recorded at least one Single in each of his last eight appearances with his team as a road underdog against the Twins.
• Yoan Moncada has scored at least one run in seven of his last eight appearances with his team as an underdog against the Twins.

Angels vs Twins Prediction 

Minnesota wasn’t able to complete the series sweep over the White Sox on Thursday, but they still picked up a much needed series win and will look to keep the momentum here. The Twins are 6-6 at home this year, while the Angels are 7-8 on the road. Los Angeles hasn’t played their best over the last two series and they will have Hendricks on the mound, who I don’t trust at all. On the other side, Minnesota is starting Lopez, who has been dominant in three starts this year. Take the Twins -1.5 in this contest. 

David Racey's Pick: Twins -1.5