Chicago White Sox vs Kansas City Royals Prediction 5/5/25 MLB Picks
Kansas City Royals (19-16) vs Chicago White Sox (10-24)
Game Info: Monday, May 5, 2025 at 7:40 pm (Kauffman Stadium)
S. Smith (R) vs C. Ragans (L)
Betting Odds: Kansas City Royals -245 / Chicago White Sox +200 --- Over/Under: 8 Click Here for the Latest Odds
Where to Watch: MLB.TV
The Chicago White Sox and Kansas City Royals meet Monday in MLB action at Kauffman Stadium. Here’s a Chicago White Sox vs Kansas City Royals Prediction. This article will include a Chicago White Sox vs Kansas City Royals Pick.
Chicago White Sox Betting Preview
The Chicago White Sox are 10-24 on the year and play the Marlins, Reds, and Cubs next. The Chicago White Sox are batting .216 on the season, have a .297 OBP, and a .328 slugging percentage. The Chicago White Sox pitching staff has a 4.16 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 30 hits and 10 RBI, while Miguel Vargas and Luis Robert Jr. have combined for 48 hits and 27 RBI.
Shane Smith gets the ball for the Chicago White Sox, and he is 1-1 with a 2.23 ERA and 26 strikeouts this season. This will be Smith’s first career game against the Kansas City Royals.
Kansas City Royals Betting Preview
The Kansas City Royals are 19-16 on the year and play the Red Sox, Astros, and Cardinals next. The Kansas City Royals are batting .237 on the season, have a .297 OBP, and a .360 slugging percentage. The Kansas City Royals pitching staff has a 3.16 ERA and a 1.20 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 41 hits and 17 RBI while Maikel Garcia and Salvador Perez have combined for 68 hits and 30 RBI.
Cole Ragans gets the ball for the Kansas City Royals, and he is 1-1 with a 4.40 ERA and 46 strikeouts this season. Ragans is 1-0 with a 0.00 ERA and 10 strikeouts in his career against the Chicago White Sox.
Why the Kansas City Royals will win
- The White Sox have lost each of their last 10 night games against AL Central opponents that held a winning record.
- The Royals have won 15 of their last 16 games at Kauffman Stadium against AL Central opponents that held a losing record.
- The White Sox have failed to cover the run line in each of their last six games against the Royals at Kauffman Stadium following a win.
- The favorites have covered the run line in each of the White Sox's last five games at Kauffman Stadium.
- The White Sox have trailed after 5 innings in eight of their last 10 games against AL Central opponents that held a winning record.
Why the Chicago White Sox will win
- The White Sox have won three of their last four games as underdogs.
- The Royals have lost five of their last six night games against American League opponents following a road win.
- The Royals have failed to cover the run line in nine of their last 10 night games against AL Central opponents.
- The White Sox have covered the run line in each of their last four games as road underdogs.
Kansas City Royals Player Prop Facts
- Bobby Witt Jr. has recorded a Double in five of the Royals' last six games against AL opponents at Kauffman Stadium.
- Maikel Garcia has scored at least one run in each of the Royals' last six games against the White Sox.
- Bobby Witt Jr. has recorded at least one Single in each of the Royals' last eight games as favorites against the White Sox.
- Salvador Perez has recorded at least one hit in each of his last seven appearances against opponents that held a losing record.
- MJ Melendez has hit a home run in three of his last four appearances against the White Sox at Kauffman Stadium.
- Hunter Renfroe has recorded at least one RBI in seven of the Royals' last eight games against the White Sox.
- Maikel Garcia ranks 9th amongst qualified players for Batting Average (.319) this season.
Chicago White Sox Player Prop Facts
- Andrew Vaughn has hit a home run in two of the White Sox's last three games against the Royals.
- Luis Robert has recorded an RBI in four of the White Sox's last five games as underdogs against AL opponents.
- Andrew Vaughn has recorded at least one hit in each of his last 10 Monday appearances.
- Andrew Benintendi has recorded at least one Single in seven of his last eight appearances at Kauffman Stadium against AL Central opponents that held a winning record.
- Andrew Benintendi has scored a run in each of his last five appearances with the White Sox as underdogs.
- Josh Rojas has recorded a Double in three of his last four appearances in night games against AL Central teams that held a winning record.
Chicago White Sox vs Kansas City Royals Prediction
The White Sox have cashed some nice underdog tickets recently, but it’s still not enough to have me looking in their direction. The White Sox have been the worst team in baseball these last two years, and they’re 14 games below a .500 record this year. The White Sox do nothing well on either side of the ball, and three wins in their last four games don’t change much. The Royals have caught fire these last couple of weeks, and Ragans misses bats at an elite level. As I've said before, I have no use for the White Sox. Give me the Royals and the RL for max betting value.
Randy’s Pick Kansas City Royals -1.5
AUTHOR: Randy Chambers

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