Miami Marlins vs Seattle Mariners Prediction 4/25/25 MLB Picks

Seattle Mariners (14-11) vs Miami Marlins (11-13)

Game Info: Friday, April 25, 2025 at 9:40 pm (T-Mobile Park)

C. Quantrill (R) vs L. Gilbert (R)

Betting Odds: Seattle Mariners -270 / Miami Marlins +210 --- Over/Under: 7.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

The Miami Marlins and the Seattle Mariners meet Friday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Miami Marlins vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Miami Marlins will send out Cal Quantrill for the start here and Quantrill is 1-2 with an 8.31 ERA and 8 strikeouts this season. In his career, Quantrill is 0-1 with a 4.34 ERA and 13 strikeouts against Seattle. Logan Gilbert will get the start for the Mariners here and Gilbert is 1-1 with a 2.63 ERA and 41 strikeouts this season. In his career, Gilbert is 2-0 with a 0.66 ERA and 11 strikeouts this season.

Miami Marlins Recap

The Miami Marlins will try to rebound after falling short in Wednesday’s series finale against the Cincinnati Reds by a final score of 5-2 to slip to 11-13 on the year. After this series, the Marlins will head on the road again for a series against the Los Angeles Dodgers.

Marlins Have Three-Game Win Streak Snapped

Xavier Edwards leads the Marlins with 28 hits including 3 doubles and a team-high 6 stolen bases while Graham Pauley has 5 doubles. Otto Lopez has 20 hits with 5 doubles and a pair of home runs with 10 RBIs and Matt Mervis has a team-high 7 home runs and 14 RBIs so far this year. Kyle Stowers has 23 hits with 3 doubles, a triple, 2 home runs and 15 RBIs but also leads the Marlins with 30 strikeouts so far this season. Griffin Conine’s also chipped in 18 hits with a team-high 7 doubles as well this season.

Why the Miami Marlins will win

  • The Marlins have won each of their last four games as underdogs against American League opponents.
  • The Mariners have lost four of their last five games as favorites against National League opponents following a road win.
  • The Mariners have failed to cover the run line each of their last six night games against teams that held a losing record.
  • The Marlins have covered the run line in each of their last four games as underdogs against American League opponents following a home loss.

Miami Marlins Player Prop Facts

  • Jesus Sanchez has hit a home run in two of his last three appearances against AL West opponents.
  • Otto Lopez has scored at least one run in three of the Marlins' last four games.
  • Jesus Sanchez has recorded at least one Single in each of his last seven appearances after not playing the previous day.
  • Cal Quantrill has recorded four or more strikeouts in each of his last four road appearances against AL opponents.
  • Jesus Sanchez has recorded at least one hit in each of his last eight appearances after not playing the previous day.
  • Matt Mervis ranks T8th in the league in Home Runs (7) this season.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their 4-3 win over the Boston Red Sox on Thursday to improve to 14-11 on the year. After this series, the Mariners will square off against the Los Angeles Angels in a division series.

Mariners Win Fifth Straight Series

Jorge Polanco has 17 hits including 3 home runs and 12 RBIs while Cal Raleigh has 16 hits with 3 doubles, a team-high 8 home runs and 11 RBIs. Randy Arozarena has 14 hits with 6 doubles, 4 home runs, a team-high 14 RBIs and 6 stolen bases. Julio Rodriguez also has 14 hits with a pair of triples, 3 home runs, 8 RBIs and 5 stolen bases. Dylan Moore has 4 homers and 4 stolen bases as well this season.

Why the Seattle Mariners will win

  • The Marlins have lost each of their last six road games against AL West opponents that held a winning record.
  • The Mariners have won nine of their last 10 games after playing the previous day.
  • The Mariners have covered the run line in nine of their last 10 games after playing the previous day.
  • The Marlins have failed to cover the run line in each of their last six night games against AL West opponents following a loss.

Seattle Mariners Player Prop Facts

  • Randy Arozarena has recorded a Double in three of the Mariners' last four games against NL opponents.
  • Cal Raleigh has hit a home run in each of the Mariners' last three home games.
  • Luke Raley has recorded at least one RBI in each of his last four home appearances against NL opponents.
  • Jorge Polanco has recorded at least one Single in each of his last seven appearances in night games against teams that held a losing record.
  • Logan Gilbert has recorded nine or more strikeouts in three of his four previous home appearances against NL opponents that held a losing record.
  • Randy Arozarena has scored at least one run in each of his last seven appearances in night games against NL East teams that held a losing record.
  • Logan Gilbert has recorded a win in three of his last four appearances with the Mariners as favorites against NL opponents.
  • Victor Robles has recorded a hit in each of his last nine home appearances against the Marlins.
  • Cal Raleigh ranks T1st in the league in Home Runs (9) this season.

Total Runs Facts

  • Eight of the Marlins' last nine night games against American League opponents have gone OVER the total runs line.
  • Four of the Mariners' last five games have gone OVER the total runs line.

Miami Marlins vs. Seattle Mariners Prediction

I’m going to take a shot on the Marlins here. I think Logan Gilbert is a fantastic pitcher, and he has great numbers in his career against the Marlins. However, The Mariners, despite winning five series in a row, have lost game one in each of their last three series before coming on strong as the series progresses. Julio Rodriguez is the only Mariners with solid career numbers against Quantrill, but other key bats like Randy Arozarena, Jorge Polanco and others are .111 or 0-fer. The Marlins’ bats have been solid out of the gate and if the Mariners get caught again we could have a nice payday attached. Give me the Marlins here.

Chris’s Pick Miami Marlins +210

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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