Houston Astros vs Kansas City Royals Prediction 4/25/25 MLB Picks

Kansas City Royals Betting Preview

The Kansas City Royals are 12-14 on the year and play the Rays, Orioles, and White Sox next. The Kansas City Royals are batting .221 on the season, have a .290 OBP, and a .320 slugging percentage. The Kansas City Royals pitching staff has a 3.52 ERA and a 1.26 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 30 hits and 10 RBI while Maikel Garcia and Salvador Perez have combined for 46 hits and 24 RBI.

Seth Lugo gets the ball for the Kansas City Royals, and he is 1-3 with a 3.90 ERA and 21 strikeouts this season. Lugo is 1-2 with a 5.24 ERA and 19 strikeouts in his career against the Houston Astros.

Why the Kansas City Royals will win

• The Astros have lost seven of their last eight games as road favorites following a home win.
• The Royals have won each of their last 13 Friday home games against American League opponents.
• The Royals have covered the run line in each of their last eight Friday night home games against American League opponents.
• The Astros have failed to cover the run line in eight of their last nine games as road favorites following a home win.
• The Astros have trailed after 5 innings in three of their last four night games against opponents that held a losing record.

Why the Houston Astros will win

• The Royals have lost each of their last eight night games against American League opponents.
• The favorites have won each of the Royals' last eight games at Kauffman Stadium.
• The Astros have covered the run line in eight of their last nine night games against American League opponents.
• The Royals have failed to cover the run line in seven of their last eight games as underdogs following a home win.
• The Royals have trailed after 5 innings in five of their last six games as underdogs against AL West opponents.
• The Royals have trailed after 3 innings in six of their last eight games as home underdogs against American League opponents.

Kansas City Royals Player Prop Facts

• Bobby Witt Jr. has hit a home run in each of the Royals' last two games as underdogs against the Astros.
• Bobby Witt Jr. has recorded a Double in four of the Royals' last five games against AL opponents at Kauffman Stadium.
• Vinnie Pasquantino has recorded at least one RBI in 11 of his last 13 appearances at Kauffman Stadium against AL opponents that held a winning record.
• Michael Massey has recorded at least one Single in each of his last six appearances at Kauffman Stadium against AL West opponents that held a winning record.
• Bobby Witt Jr. has scored at least one run in each of the Royals' last 13 Friday night games against AL opponents that held a winning record.
• Seth Lugo has recorded four or more strikeouts in 10 of his last 11 appearances in night games against AL teams that held a winning record.
• Vinnie Pasquantino has recorded at least one hit in each of his last eight home appearances against AL West opponents that held a winning record.

Houston Astros Player Prop Facts

• Isaac Paredes has hit a home run in three of the Astros' last five games as favorites against AL opponents.
• Jose Altuve has recorded a Double in three of the Astros' last four games at Kauffman Stadium.
• Yordan Alvarez has recorded at least one RBI in seven of his last eight appearances in night games against AL Central teams that held a losing record.
• Yainer Diaz has scored a run in each of the Astros' last six games as favorites against the Royals.
• Jeremy Pena has recorded a Single in each of the Astros' last seven games as favorites against AL opponents.
• Jeremy Pena has recorded at least one hit in each of the Astros' last 11 night games.

Houston Astros vs Kansas City Royals Prediction

You can make a case for either the Astros or Royals as they’re putting together their best week of the season. The difference here is the Astros have been more impressive against better competition while the Royals took advantage of the Rockies. If you’re not paying attention, the Rockies suck. Also, the Royals played two games yesterday and played a total of eight pitchers. That can really throw a bullpen off without an off day. Wesneski has given the Astros a chance in all four starts, allowing 16 hits and 10 runs in 23 innings. I’ll lay the cheap price with the Astros on the road.