St. Louis Cardinals vs New York Mets Prediction 4/19/25 MLB Picks

Recent betting trends and streaks involving the New York Mets

Recent betting trends and streaks involving the Saint Louis Cardinals

Recent betting trends in games played between the Saint Louis CardinalsvsNew York Mets

A summary that ties it all together and produces a favorable betting outcome for Saint Louis Cardinals vs New York Mets game

New York Mets Preview

The New York Mets have a 13-7 record this season and are sitting on the first place of the NL East. The Mets have a 7-1 home record and are 6-14 in over/under. They are coming off a 5-4 home victory over the Cardinals, having won both games of this series. Under is 5-2 in their last 7 games, and are playing the Phillies and the Nationals next. The Mets have a .224 batting average this season, .303 OBP and .388 slugging percentage. New York’s pitching staff has a 2.39 ERA and 1.16 WHIP.  Pete Alonso leads the Mets with 24 hits, 21 RBI, 5 home runs and a team-high .348 batting average.

Kodai Senga (R) will take the mound for the Mets, and he has a 2-1 record, 1.06 ERA and 1.00 WHIP. He is coming off back-to-back starts where he had zero earned runs in 12 innings of work. In his two starts against the Cardinals in his career, he has a 3.41 ERA.

Saint Louis Cardinals Preview

The Saint Louis Cardinals have a 9-11 record this season and are sitting on the 4th place of the NL Central. The Cardinals have a 1-7 road record and are 11-8 in over/under They are coming off a 4-5 road defeat by the Mets, and are 7-2 to the under in their last 9 games. They are playing the Braves and the Brewers next. The Cardinals have a .270 batting average this season, .337 OBP and .416 Slugging percentage. Saint Louis’ pitching staff has a 4.11 ERA and 1.17 WHIP. Brendan Donovan leads the Cardinals with 30 hits, 13 RBI, and a team-high .380 batting average.

Matthew Liberatore (L) will take the mound for the Cardinals, and he has a 1-1 record, 3.93 ERA and 0.98 WHIP. He is coming off a shutout against the Phillies in 6 innings of work. In his only previous start against the Mets back in 2023, he struggled with 5 earned runs in just 4 innings pitched.  

Why the New York Mets will win

• The Mets have won each of their last six games against the Cardinals.
• The Cardinals have lost seven of their last eight road games.
• The Mets have covered the run line in five of their last six games against the Cardinals.
• The Cardinals have failed to cover the run line in three of their last four day games against NL East opponents.
• The Mets have led after 3 innings in three of their last four day games against NL Central opponents.
• The Mets have led after 5 innings in four of their last five games against the Cardinals.

Why the St. Louis Cardinals will win

• The Cardinals have won eight of their last nine games as underdogs against National League opponents following a loss.
• The Mets have lost three of their last four games as favorites following a win.
• The Cardinals have covered the run line in each of their last nine games as underdogs against National League opponents following a loss.
• The Mets have failed to cover the run line in each of their last six games as home favorites against the Cardinals following a win.
• The Cardinals have led after 3 innings in three of their last four games at Citi Field against National League opponents that held a winning record.
• The Mets have trailed after 5 innings in four of their last five day games against opponents that held a losing record.

Total Runs Facts

• Each of the Cardinals' last seven day games against NL East opponents have gone UNDER the total runs line.
• Each of the Mets' last four day games after playing the previous day have gone UNDER the total runs line.
• The 'Inning 1 UNDER 0.5 runs' market has hit in eight of the Mets' last nine games.
• The 'Inning 1 UNDER 0.5 runs' market has hit in seven of the Cardinals' last eight games as underdogs against NL East opponents.

Matchup/League Facts

• The Mets rank T1st in the league for triples this season (6).
• The Mets rank 1st in the league for ERA this season (2.39).
• The Cardinals rank 2nd in the league for hits this season (191).
• The Cardinals rank 2nd in the league for batting average this season (.270).

Saint Louis Cardinals vs New York Mets Prediction

The Mets have won the first two games of this series by 4-1 and 5-4, and are 6-0 in their 6 overall meetings against the Cardinals. The Mets are 3-1 in their last 4 meetings in New York.  Under is 4-2 in their last 6 meetings.

In this Saint Louis Cardinals vs New York Mets Prediction, the Mets are coming as -170 home favorites. The Mets are rightfully favored, as they have a better overall record, they have been terrific at home, while the Cardinals have been terrible on the road. The Mets have also dominated the Cardinals in recent meetings and are now putting their ace on the mound in Kodai Senga. Senga is coming of back-to-back shutouts, so I see no way of backing the Cardinals in this one. Liberatore has been ok this season, but he was torched in his last start against the Mets in 2023, and the Mets have one of the best bullpens in the MLB. Take the Mets on the runline in this one.