San Francisco Giants vs Philadelphia Phillies Prediction 4/17/25 MLB Picks

Giants Trying For Series Win

Jung Hoo Lee leads the Giants with 21 hits including a team-high 9 doubles along with 3 home runs and 12 RBIs with 3 stolen bases while Heliot Ramos has 16 hits with 5 doubles, 3 home runs and 9 RBIs. Wilmer Flores also has a team-high 6 home runs and 21 RBIs while Mike Yastrzemski has 3 home runs with 9 RBIs and 4 doubles and Tyler Fitzgerald has a team-high 4 stolen bases as well on the year.

Why the San Francisco Giants will win

• The Giants have won nine of their last 12 games as underdogs after playing the previous day.
• The Phillies have lost four of their last six games as favorites.
• The Giants have covered the run line in each of their last four day games against National League opponents.
• The Phillies have failed to cover the run line in five of their last six day games against teams that held a winning record.

Philadelphia Phillies Recap

The Philadelphia Phillies will try to bounce back after falling flat in Wednesday’s beatdown loss. After this set, the Phillies will square off against the Miami Marlins in a division series at home.

Phillies Looking To Salvage Series Split

Nick Castellanos has a team-high 19 hits with 5 doubles including 3 home runs and 11 RBIs while Kyle Schwarber has 16 hits with a team-high 6 home runs and 12 RBIs as well on the year. Bryce Harper and Trea Turner each have a team-high 4 stolen bases, with Turner logging 3 doubles while Harper has 3 home runs and 7 RBIs. Max Kepler has 4 doubles and Bryson Stott has 3 doubles while J.T. Realmuto also has 4 stolen bases as well this season.

Why the Philadelphia Phillies will win

• The Phillies have won each of their last 11 home games against National League opponents following a home loss.
• The Giants have lost five of their last six games against National League opponents following a win.
• The Phillies have covered the run line in each of their last four games as home favorites against NL West opponents following a loss.
• The Giants have failed to cover the run line in four of their last five day games against the Phillies at Citizens Bank Park following a win.

Total Runs Facts

• Each of the Giants' last seven games have gone OVER the total runs line.
• Each of the Phillies' last six day games as favorites have gone UNDER the total runs line.

San Francisco Giants vs. Philadelphia Phillies Prediction

I’m going to side with the Phillies here. I know the Giants have been a team that can provide a lot of value on the road and they will plenty this season I think. However, Jordan Hicks is probably one of my least favorite starting options in this Giants’ rotation, as he throws a lot of heat, but gasses himself out too early, and at times gets lit up because of it like he did in his last start. He got hit hard by the Phillies in his lone career start against them, and I think Hicks gets roughed up again. I much prefer the Giants against righties than lefties right now, and Cristopher Sanchez is looking like one of the better lefties in baseball right now. I’ll roll with the Phillies to earn the split in this one.