Cincinnati Reds vs San Francisco Giants Prediction 4/7/25 MLB Picks

San Francisco Giants (8-1) vs Cincinnati Reds (3-7)

Game Info: Monday, April 7, 2025 at 9:45 pm (Oracle Park)

H. Greene (R) vs L. Webb (R)

Betting Odds: San Francisco Giants -148 / Cincinnati Reds +124 --- Over/Under: 7 Click Here for the Latest Odds

Where to Watch: MLB.TV

The Cincinnati Reds and San Francisco Giants meet Monday in MLB action at Oracle Park. Here’s a Cincinnati Reds vs San Francisco Giants Prediction. This article will include a Cincinnati Reds vs San Francisco Giants Pick.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 3-7 on the year and play the Pirates, Mariners, and Orioles next. The Cincinnati Reds are batting .210 on the season, have a .269 OBP, and a .352 slugging percentage. The Cincinnati Reds pitching staff has a 3.41 ERA and a 1.02 WHIP. TJ Friedl leads the Cincinnati Reds with 11 hits and 4 RBI, while Elly De La Cruz and Gavin Lux have combined for 17 hits and 13 RBI. 

Hunter Greene gets the ball for the Cincinnati Reds, and he is 0-1 with a 2.25 ERA and 16 strikeouts this season. Greene is 2-0 with a 1.10 ERA and 25 strikeouts in his career against the San Francisco Giants.

San Francisco Giants Betting Preview

The San Francisco Giants are 8-1 on the year and play the Yankees, Phillies, and Angels next. The San Francisco Giants are batting .238 on the season, have a .309 OBP, and a .421 slugging percentage. The San Francisco Giants pitching staff has a 2.85 ERA and a 1.24 WHIP. Heliot Ramos leads the San Francisco Giants with 12 hits and 9 RBI while Jung Hoo Lee and Matt Chapman have combined for 20 hits and 11 RBI.

Logan Webb gets the ball for the San Francisco Giants, and he is 1-0 with a 3.00 ERA and 11 strikeouts this season. Webb is 2-2 with a 2.13 ERA and 35 strikeouts in his career against the Cincinnati Reds.

Why the San Francisco Giants will win

  • The Giants have won each of their last six games after playing the previous day.
  • The Reds have lost five of their last six games after playing the previous day.
  • The Giants have covered the run line in each of their last nine Monday night games.
  • The Reds have failed to cover the run line in five of their last six games against NL West opponents.
  • The Reds have trailed after 5 innings in five of their last six games.

Why the Cincinnati Reds will win

  • The Reds have won each of their last seven Monday games as underdogs.
  • The Giants have lost seven of their last eight games against NL Central opponents following a win.
  • The Reds have covered the run line in each of their last nine Monday night games.
  • The Giants have failed to cover the run line in each of their last four games against National League opponents following a home win.
  • The Giants have trailed after 5 innings in seven of their last nine night games at Oracle Park against National League opponents.

Matchup/League Facts

  • The Reds rank T26th in the league for doubles this season (10).
  • The Reds rank 5th in the league for opponent batting average this season (.201).

Cincinnati Reds vs San Francisco Giants Prediction

The Reds are better than what they’ve shown through their first 10 games but at some point, we need to see results. The Reds have scored three or fewer runs in seven of their 10 games and have 81 strikeouts. I don’t believe the Giants are as good as their record indicates but they’re rolling right now and are stringing together offense. Webb is also on the mound for the Giants, and through 68 starts at Oracle Park, he has a 2.78 ERA and 1.11 WHIP. This isn’t a spot where the Reds find their offensive spark. Give me the Giants and the reasonable price.

Randy’s Pick San Francisco Giants -148

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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