Chicago White Sox vs Detroit Tigers Prediction 4/5/25 MLB Picks

Detroit Tigers Betting Preview

The Detroit Tigers are 3-4 on the year and play the Yankees, Twins, and Brewers next. The Detroit Tigers are batting .269 on the season, have a .348 OBP, and a .454 slugging percentage. The Detroit Tigers' pitching staff has a 4.92 ERA and a 1.11 WHIP. Riley Greene leads the Detroit Tigers with 11 hits and 4 RBI, while Spencer Torkelson and Zach McKinstry have combined for 15 hits and 5 RBI.

Reese Olson gets the ball for the Detroit Tigers, and he is 0-1 with a 7.71 ERA and 5 strikeouts this season. Olson is 2-2 with a 2.16 ERA and 15 strikeouts in his career against the Chicago White Sox.

Why the Detroit Tigers will win

• The White Sox have lost 11 of their last 12 road games against AL Central opponents that held a losing record.
• The Tigers have won eight of their last 10 games against the White Sox following a win.
• The White Sox have failed to cover the run line in seven of their last eight road games against AL Central opponents following a loss.
• The Tigers have covered the run line in each of their last three games at Comerica Park.
• The Tigers have led after 3 innings in three of their last four games against American League opponents.
• The Tigers have led after 5 innings in three of their last four games.

Why the Chicago White Sox will win

• The White Sox have won seven of their last eight games as road underdogs against the Tigers following a road loss.
• The Tigers have lost seven of their last nine games as home favorites against the White Sox, following a home win.
• The White Sox have covered the run line in each of their last eight games as road underdogs against the Tigers following a road loss.
• The Tigers have failed to cover the run line in 10 of their last 11 games as home favorites against the White Sox following a win.

Chicago White Sox vs Detroit Tigers Prediction

I’m not sure Olson is a pitcher who deserves to be this big of a favorite, and he wasn’t great in his season debut. However, this line has more to do with the White Sox than anything else. The White Sox were expected to be the worst team in baseball, and they’re wasting no time looking like just that. The White Sox can’t score runs easily, and they just find ways to lose even in games where they compete. The Tigers have won three of their last four games, and the offense is picking up. I’m going to do a lot of fading the White Sox this season, and that’s the case here as well. Give me the Tigers and the RL for maximum betting value.