Seattle Mariners vs San Francisco Giants Prediction 4/4/25 MLB Picks

Mariners Avoid Sweep Against Detroit

Victor Robles and Jorge Polanco share Seattle’s team lead with 6 hits, with Robles logging 3 doubles and 3 RBIs while Polanco has a home run and 4 RBIs. Randy Arozarena also has 4 hits with a pair of doubles and a pair of solo home runs while Julio Rodriguez has 4 hits with a triple and a home run as well this season.

Why the Seattle Mariners will win

• The Mariners have won eight of their last nine games as road underdogs against National League opponents following a home win.
• The Giants have lost four of their last five games as favorites against AL West opponents following a win.
• The road team has covered the run line in each of the Giants' last nine games.
• The Giants have failed to cover the run line in each of their last eight Friday games as home favorites against American League opponents.

Seattle Mariners Player Prop Facts

• Luke Raley has hit a home run in six of his last seven appearances after not playing the previous day.
• J.P. Crawford has recorded a Double in four of his last five appearances in day games against NL West teams that held a winning record.
• Luke Raley has recorded at least one RBI in each of his last four appearances against NL West opponents.
• Cal Raleigh has recorded a Single in each of the Mariners' last six day games against opponents that held a winning record.
• Luke Raley has scored at least one run in each of his last seven appearances after not playing the previous day.
• Luke Raley has recorded at least one hit in each of his last nine appearances after not playing the previous day.

San Francisco Giants Recap

The San Francisco Giants enter this game looking to keep the ball rolling after pulling off the sweep of the Houston Astros thanks to a 6-3 win in Wednesday’s series finale. After this series, the Giants will welcome the Cincinnati Reds to town for an interleague series.

Giants Win 4th In A Row

Heliot Ramos leads the Giants with 7 hits including 6 extra base hits with 3 doubles, 3 home runs and 7 RBIs but also has a team-high 11 strikeouts so far this season. Wilmer Flores also has 5 hits with a team-high 4 home runs and 10 RBIs while Jung Hoo Lee has 3 doubles of his own in addition to a .278 batting average so far this season.

Why the San Francisco Giants will win

• The Giants have won each of their last six games against American League opponents.
• The Mariners have lost four of their last five games against the Giants following a home win.
• The Giants have covered the run line in each of their last seven games against AL West opponents.
• The Mariners have failed to cover the run line in seven of their last eight games against NL West opponents.

San Francisco Giants Player Prop Facts

• Heliot Ramos has hit a home run in each of the Giants' last three games as favorites.
• Matt Chapman has recorded at least one Double in four of his last five appearances with his team as a home favorite against the Mariners.
• Justin Verlander has recorded a win in six of his last seven home appearances against the Mariners.
• Heliot Ramos has recorded at least one RBI in five of the Giants' last six games as favorites against AL opponents.
• Justin Verlander has recorded six or more strikeouts in 36 of his last 41 appearances against AL West opponents that held a losing record.
• Matt Chapman has recorded a Single in eight of the Giants' last nine games against opponents that held a losing record.
• Willy Adames has scored at least one run in each of his last five appearances against AL West opponents that held a losing record.
• Matt Chapman has recorded at least one hit in each of his last eight appearances after not playing the previous day.
• Wilmer Flores ranks T3rd in the league in Home Runs (4) this season.

Total Runs Facts

• Each of the Giants' last five games as favorites against AL West opponents have gone UNDER the total runs line.
• Five of the Mariners' last six day games against National League opponents have gone OVER the total runs line.

Seattle Mariners vs. San Francisco Giants Prediction

I’m on the San Francisco Giants here. I get the allure of backing a team like Seattle in certain spots, but right now for me, the Mariners are a hard team to get behind because of an offense that stalls out far too often for my liking, which was a problem from last year that needed to be addressed, and for Seattle, it wasn’t. The pitching is fine, although it’s weird they have two Luis Castillos on the roster, but at a certain point, last I checked, the rules of baseball are that you have to score more runs than the other team and the pitcher can only do so much. Justin Verlander’s the better arm here and the Giants have gotten off to quite the start at the dish as well this season. I’ll roll with San Francisco in this one.