Arizona Diamondbacks vs Washington Nationals Prediction 4/4/25 MLB Picks

Washington Nationals Betting Preview

The Washington Nationals are 1-5 on the year and play the Dodgers, Marlins, and Pirates next. The Washington Nationals are batting .213 on the season, have a .279 OBP, and a .406 slugging percentage. The Washington Nationals pitching staff has a 5.02 ERA and a 1.67 WHIP. Keibert Ruiz leads the Washington Nationals with 8 hits and 5 RBI while Nathaniel Lowe and CJ Abrams have combined for 14 hits and 10 RBI.

Jake Irvin gets the ball for the Washington Nationals, and he is 0-0 with a 3.60 ERA and 2 strikeouts this season. Irvin is 0-2 with a 4.80 ERA and 9 strikeouts in his career against the Arizona Diamondbacks.

Why the Washington Nationals will win

• The underdogs have won each of the last three games between the Diamondbacks and Nationals at Nationals Park.
• The Diamondbacks have lost six of their last eight games as favorites following a road loss.
• The Nationals have covered the run line in 12 of their last 13 Friday night games against National League opponents.
• The Diamondbacks have failed to cover the run line in six of their last seven night games against National League opponents that held a losing record.

Why the Arizona Diamondbacks will win

• The Nationals have lost each of their last 14 night games following a road loss.
• The Diamondbacks have won each of their last six night games against NL East opponents that held a losing record.
• The Diamondbacks have covered the run line in each of their last nine night games at Nationals Park following a loss.
• The Nationals have failed to cover the run line in six of their last seven games.
• The Nationals have trailed after 3 innings in four of their last five home games against NL West opponents that held a winning record.
• The Nationals have trailed after 5 innings in each of their last five games at Nationals Park against NL West opponents that held a winning record.

Arizona Diamondbacks vs Washington Nationals Prediction

The Diamondbacks held their own against the Yankees and that’s a nice confidence boost moving forward. The Nationals have looked like one of the worst teams in baseball, as they’re not hitting and their pitching staff has been getting tattooed. The Nationals have allowed four or more runs in five of their first six games. That’s not great when going up against one of the better lineups in baseball. Irvin has been hittable for most of his career and the Nats have lost seven of his last eight games. The line is reasonable. Give me the Diamondbacks on Friday afternoon.