Minnesota Twins vs St. Louis Cardinals Prediction 3/30/25 MLB Picks

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 2-0 this season after they won game two in this series by a score of 5-1 yesterday. St. Louis scored in the first inning on an Arenado RBI single and added three more in the sixth to take the lead. The Cardinals recorded 10 hits in the game, but they did commit an error. Lars Nootbaar went 2-3 with two RBI’s in the win, while Donovan, Arenado, and Herrera added one RBI each. St. Louis started Erick Fedde, who allowed one earned run and two hits over 6.0 innings, while Fernandez, Romero, and Maton combined for three shutout innings out of the bullpen. 

Last year, the St. Louis pitching staff had a 4.04 ERA with a 1.26 WHIP and a .249 opponent batting average, while the offense scored 672 runs with a .248 batting average and a .312 on base percentage. The Cardinals were ranked 22nd in the MLB in runs scored last season and need to find more consistent hitting this year. St. Louis was led by Paul Goldschmidt last season, but he is no longer with the team, while Alec Burleson hit .269 with 21 home runs and 78 RBI’s. The projected starting pitcher for St. Louis is Andre Pallante, who was 8-8 with a 3.78 ERA and a 1.30 WHIP over 121.1 innings pitched last year for the Cards. 

Why the Cardinals will beat the Twins 

• The Twins have lost nine of their last 10 games as favorites.
• The Cardinals have won each of their last four games as home underdogs.
• The Twins have failed to cover the run line in each of their last six games.
• The underdogs have covered the run line in each of the Cardinals' last six games.
• The Cardinals have led after 3 innings in three of their last four games at Busch Stadium against American League opponents that held a losing record.
• The Cardinals have led after 5 innings in three of their last four games as home underdogs.

Why the Twins will beat the Cardinals 

• The Cardinals have lost four of their last five games against the Twins at Busch Stadium following a home win.
• The Twins have won four of their last five games at Busch Stadium against NL Central opponents that held a winning record.
• The Twins have covered the run line in 17 of their last 21 road games against NL Central opponents that held a winning record.
• The Cardinals have failed to cover the run line in each of their last five Sunday games at Busch Stadium.

Total Runs Facts

• Five of the Twins' last six games as favorites against the Cardinals have gone UNDER the total runs line.
• Seven of the Cardinals' last nine home games after playing the previous day have gone UNDER the total runs line.
• The 'Inning 1 OVER 0.5 runs' market has hit in each of the Twins' last four games as favorites against National League opponents.
• The 'Inning 1 UNDER 0.5 runs' market has hit in 10 of the Cardinals' last 12 games at Busch Stadium.

St. Louis Cardinals Player Prop Facts

• Brendan Donovan has recorded at least one RBI in each of the Cardinals' last four games as underdogs.
• Lars Nootbaar has hit a home run in three of the Cardinals' last six games.
• Nolan Arenado has recorded at least one Single in each of his last eight appearances.
• Nolan Arenado has scored a run in each of the Cardinals' last five games as home underdogs.
• Nolan Arenado has recorded at least one hit in each of the Cardinals' last nine games against AL Central opponents.

Minnesota Twins Player Prop Facts

• Ryan Jeffers has hit a home run in two of his last three road appearances against NL Central opponents that held a winning record.
• Trevor Larnach has recorded at least one Single in each of his last six appearances with the Twins as favorites.
• Trevor Larnach has scored at least one run in six of his last seven appearances in day games against NL teams that held a winning record.
• Bailey Ober has recorded six or more strikeouts in five of his last six appearances.
• Trevor Larnach has recorded at least one hit in each of his last six appearances.
• Willi Castro has recorded an RBI in five of the Twins' last six games as favorites against NL Central opponents.
• Willi Castro has recorded a Double in each of the Twins' last three road games against NL opponents.

Minnesota Twins vs St. Louis Cardinals Prediction 

Minnesota comes into this matchup trying to avoid a third straight loss to open the season, but they need their bats to wake up, as they have scored a total of four runs in the first two games. St. Louis has scored five runs in each of the first two games of the series and they will turn to Pallante, who was very good last season. Minnesota will counter with Ober, who also had a very nice 2024 season and had a WHIP of just 1.00. I think we are going to see another lower scoring game here and I like the under in this game.