Baltimore Orioles vs St. Louis Cardinals Prediction MLB Picks 5/22/24

St. Louis Cardinals (21-26) vs Baltimore Orioles (29-16)

Game Info: Wednesday, May 22, 2024 at 1:15 pm (Busch Stadium)

Kyle Gibson (3-2) (4.09) vs John Means (2-0) (3.06)

Betting Odds: St. Louis Cardinals +114 / Baltimore Orioles -135 --- Over/Under: 8.5 Click Here for the Latest Odds

The Baltimore Orioles and St. Louis Cardinals meet Wednesday in MLB game 2 action at Busch Stadium. Here’s a Baltimore Orioles vs St. Louis Cardinals Prediction.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 29-16 on the season after recent wins over the Blue Jays and Mariners. The Baltimore Orioles have scored 12 runs in their last 3 games and 3 or fewer runs in 5 of their last 7 games. The Baltimore Orioles have lost 4 of their last 6 games when scoring 3 or fewer runs. Adley Rutschman leads the Baltimore Orioles with 55 hits and 28 RBI, while Gunnar Henderson and Jordan Westburg have combined for 95 hits and 63 RBI.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 21-26 on the year after wins over the Angels and Red Sox. The St. Louis Cardinals have scored 16 runs in their last 3 games and 4 or more runs in 6 of their last 8 games. The St. Louis Cardinals have won 6 straight games when scoring 4 or more runs. Nolan Arenado leads the St. Louis Cardinals with 48 hits and 22 RBI, while Brendan Donovan and Masyn Winn have combined for 80 hits and 34 RBI.

Baltimore Orioles vs St. Louis Cardinals Pitching Matchup

John Means gets the ball for the Baltimore Orioles, and he is 2-0 with a 3.06 ERA and 15 strikeouts this season. Means has allowed 15 hits and 6 runs in 17.2 innings this season. Means has a 0.00 ERA and .130 allowed batting average in 7 road innings. This will be Means’ second career game against the St. Louis Cardinals.

Kyle Gibson gets the ball for the St. Louis Cardinals, and he is 3-2 with a 4.09 ERA and 43 strikeouts this season. Gibson has allowed 18 hits and 9 earned runs in his last 17 innings. Gibson has a 4.80 ERA and .265 allowed batting average in 30 home innings. Gibson is 6-2 with a 3.82 ERA and 63 strikeouts in his career against the Baltimore Orioles.

Why the Baltimore Orioles will win

  • The Orioles have won nine of their last 10 games following a loss.
  • The Cardinals have lost each of their last four day games against American League opponents.
  • The Cardinals have failed to cover the run line in five of their last six day games against American League opponents.
  • The Orioles have covered the run line in 12 of their last 15 day games following a road loss.
  • The Orioles have led after 3 innings in each of their last three day games against NL Central opponents.

St. Louis Cardinals Player Prop Facts

  • Willson Contreras has scored at least one run in each of his last seven appearances at Busch Stadium.
  • Lars Nootbaar has recorded at least one RBI in four of the Cardinals' last five home games.
  • Alec Burleson has recorded at least one Single in each of his last seven appearances against AL opponents that held a winning record.
  • Lars Nootbaar has hit a home run in three of the Cardinals' last five home games.
  • Nolan Arenado has recorded at least one hit in each of his last 11 appearances with the Cardinals as home underdogs against AL opponents.
  • Willson Contreras has recorded at least one total base in each of his last 11 appearances with his team as an underdog against AL East opponents.
  • Lance Lynn has recorded five or more strikeouts in 22 of his last 23 appearances with his team as a home underdog against AL opponents.

Baltimore Orioles Player Prop Facts

  • Kyle Bradish has recorded a win in three of his last four appearances with the Orioles as favorites against NL opponents.
  • Gunnar Henderson has scored at least one run in each of the Orioles' last five road games against opponents that held a losing record.
  • Adley Rutschman has recorded at least one Single in 13 of the Orioles' last 14 games as road favorites.
  • Adley Rutschman has recorded at least one RBI in six of the Orioles' last seven day games against opponents that held a losing record.
  • Gunnar Henderson has recorded three or more total bases in each of the Orioles' last four games against the Cardinals.
  • Kyle Bradish has recorded six or more strikeouts in each of his last five appearances with the Orioles as road favorites.
  • Gunnar Henderson has hit a home run in each of the Orioles' last three games as favorites.
  • Anthony Santander has recorded at least one hit in each of the Orioles' last eight Wednesday games against opponents that held a losing record.

Matchup/League Facts

  • The St. Louis Cardinals rank 27th in the league for opponent batting average this season (.260).
  • The St. Louis Cardinals rank T26th in the league for home runs this season (39).
  • The Baltimore Orioles rank 1st in the league for hits allowed this season (334).
  • The Baltimore Orioles rank 29th in the league for walks this season (119).

Baltimore Orioles vs St. Louis Cardinals Prediction

John Means has had a limited sample size so far this season, but he's been solid through three starts, and the Orioles have won all of those games. Kyle Gibson has been hittable this season, and he's been at his worst at home through 30 innings. It's also only a matter of time before the Baltimore Orioles lineup starts to string together runs. Quick turnaround, which usually favors the home team, but we're getting the Orioles at a reasonably cheap price. Give me the O's on the road Wednesday afternoon. 

Randy’s Pick Baltimore Orioles -135

Get Premium Picks Start Winning Now »
The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

MLB Best Bets for Today Picks & Predictions Tuesday 6/25/24 | 7 Picks in 5 Minutes

18+ Has gambling become a problem for you? Call the National Problem Gambling Hotline.
1-800-522-4700 | ncpgambling.org

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.

Dismiss