Padres vs Cubs Prediction - MLB Picks 4/27/23

Chicago Cubs (13-10) vs San Diego Padres (13-13)

Game Info: Thursday, April 27, 2023 at 2:20 pm (Wrigley Field)

Hayden Wesneski (1-1) (6.23) vs Seth Lugo (2-1) (2.78)

Betting Odds: Chicago Cubs +115 / San Diego Padres -135 --- Over/Under: 8.5 Click Here for the Latest Odds

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The San Diego Padres will play the Chicago Cubs in Game 3 of their series on Thursday afternoon at Wrigley Field in Chicago, Illinois.

Padres Preview

The San Diego Padres are 13-13 this season and they have won five of their last seven games. San Diego won Game 2 of this series by a score of 5-3 on Wednesday night. The San Diego pitching staff has a 4.37 ERA, a 1.37 WHIP, and a .247 opponent batting average this year. The Padres offense has scored 97 runs with a .216 batting average and a .301 on base percentage. Xander Bogaerts is batting .326 with five home runs and 12 RBI’s for the Padres. The projected starting pitcher for San Diego is Seth Lugo, who is 2-1 with a 2.78 ERA and a 1.28 WHIP over 22.2 innings pitched this season.

Cubs Preview

The Chicago Cubs are 13-10 this season and they have lost four of their last six games. Chicago won Game 1 of this series by a score of 6-0 on Tuesday. The Chicago pitching staff has a 3.57 ERA, a 1.17 WHIP, and a .214 opponent batting average. The Cubs offense has scored 130 runs with a .276 batting average and a .347 on base percentage this season. Patrick Wisdom is batting .241 with nine home runs and 18 RBI’s for the Cubs. The projected starting pitcher for Chicago is Hayden Wesneski, who is 1-1 with a 6.23 ERA and a 1.67 WHIP over 17.1 innings pitched this year. 


San Diego is 7-1 in their last 8 game three’s of a series and 1-9 in their last 10 Thursday games. The under is 5-2-2 in San Diego’s last 9 road games. Chicago is 25-13 in their last 38 games and 17-36 in their last 53 games against the NL West. The under is 5-0 in Chicago’s last 5 Thursday games. San Diego is 5-1 in these two teams last 6 head to head meetings.


These two teams have split the first two games in this series and will be looking for the series win in this matchup. San Diego has not hit the ball very well to start the season, but they have scored five or more runs in four of their last six games. The Padres will have Seth Lugo on the mound, who has allowed five earned runs in his last 9.2 innings pitched. I like the Padres to get the win here. 

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

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