Cardinals vs Mariners Prediction - MLB Picks 4/21/23

Seattle Mariners (8-11) vs St. Louis Cardinals (8-11)

Game Info: Friday, April 21, 2023 at 10:10 pm (T-Mobile Park)

George Kirby (1-1) (3.78) vs Steven Matz (0-2) (6.48)

Betting Odds: Seattle Mariners -130 / St. Louis Cardinals +110 --- Over/Under: 8 Click Here for the Latest Odds

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The St. Louis Cardinals will play the Seattle Mariners in Game 1 of their series on Friday night at T-Mobile Park in Seattle, Washington.

Cardinals Preview

The St. Louis Cardinals are 8-11 this season and they have lost three of their last five games. St. Louis is coming off of a series loss to Arizona, where they lost two out of three games played. The St. Louis pitching staff has a 4.66 ERA, a 1.48 WHIP, and a .282 opponent batting average this year. The Cardinals offense has scored 91 runs with a .274 batting average and a .354 on base percentage. Nolan Gorman is batting .316 with five home runs and 18 RBI’s for the Cardinals. The projected starting pitcher for St. Louis is Steven Matz, who is 0-2 with a 6.48 ERA and a 1.80 WHIP over 16.2 innings pitched this season. 

Mariners Preview

The Seattle Mariners are 8-11 this season and they have lost three games in a row. Seattle is coming off of a series loss to the Brewers, where they lost all three games played. The Seattle pitching staff has a 3.64 ERA, a 1.25 WHIP, and a .228 opponent batting average. The Mariners offense has scored 85 runs with a .228 batting average and a .305 on base percentage this year. Julio Rodriguez is batting .259 with four home runs and 12 RBI’s for the Mariners. The projected starting pitcher for Seattle is George Kirby, who is 1-1 with a 3.78 ERA and a 1.26 WHIP over 16.2 innings pitched this year. 


St. Louis is 6-1 in their last 7 interleague games and 9-4 in their last 13 Friday games. The over is 4-0-1 in St. Louis’ last 5 games. Seattle is 4-1 in their last 5 Friday games and 5-12 in their last 17 game one’s of a series. The under is 4-1 in Seattle’s last 5 games following an off day. The under is 7-3-1 in these two teams last 11 head to head meetings. 


Seattle was just swept at home by Milwaukee and will look to bounce back with a win here. St. Louis is also coming off of a series loss to Arizona, where they allowed 19 runs in three games. The Cardinals will start Steven Matz, who pitched much better in his last start than he did in his first two. The Mariners will start George Kirby, who has allowed three earned runs over his last 12.1 innings pitched. I am taking the Mariners at home in this game. 

David’s Pick Mariners ML

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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