Detroit Tigers at Baltimore Orioles - 9/21/22 MLB Picks and Prediction

Baltimore Orioles (76-70) vs Detroit Tigers (56-91)

Game Info: Wednesday, September 21, 2022 at 7:05 pm (Oriole Park at Camden Yards)

Jordan Lyles (10-11) (4.70) vs Matt Manning (2-2) (3.28)

Betting Odds: Baltimore Orioles -167 / Detroit Tigers +125 --- Over/Under: 8 Click Here for the Latest Odds

Where to Watch: MASN Stream the MLB Game of the Day all season on ESPN+. Sign up now! Advertisement

The Detroit Tigers and Baltimore Orioles face off on Wednesday in an MLB showdown at Oriole Park at Camden Yards. The Tigers have won the first two games of this series. 

The Tigers come into this game with a 57-91 record overall and the pitching has been strong in each of the first two games of this series. On Tuesday they gave up two runs in the 7th inning but still held on for the 3-2 victory. Overall this season the Tigers offense has been an issue and they are averaging only 3.35 runs per game which is 30th in the league. The pitching is also ranked 20th in the league. 

On the other side of this matchup is the Orioles who sit with a 76-71 record overall and they have lost four of their last five games. In the first two games of this season, the Tigers have scored only two runs total. Gunnar Henderson finished the game with two hits and two runs. The Orioles pitching has been the strength this season averaging 4.19 runs per game which is 12th in the league. 

On the mound for the Tigers will be Matt Manning who sits with a 2-2 record and an ERA of 3.28. In his last start against the White Sox, he went seven innings giving up three hits and zero runs.

On the mound for the Orioles will be Jordan Lyles who sits with a 10-11 record and an ERA of 4.70. In his last start against the Toronto Blue Jays, he went five innings giving up five hits and four runs. 

The Orioles are 9-1 in Lyles last 10 starts on grass. The Orioles are 6-1 in their last seven home starts. The under is 5-0 in the Orioles last five Wednesday games. The under is 4-0 in the Orioles last four starts against the American League Central. 

The Orioles have lost the first two games of this series, and they will lose another one here. Lyles gave up four runs in his last start, and the Tigers will find some success scoring off him here. Look for Manning to have another strong start here, and the Tigers will secure another win.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

MLB Best Bets for Today Picks & Predictions Wednesday 9/27/23 | 7 Picks in 5 Minutes

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.