MLB Picks and Predictions for 5/26/21 - Free MLB Picks

MLB Picks and Predictions for 5/26/21 - Free MLB Picks Photo by Vincent Carchietta-USA TODAY Sports

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MLB Games on Wednesday May 26th, 2021

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We have a full slate of MLB games on Wednesday May 26th, 2021. Check out our best picks below, as well as the updated betting odds.

Baltimore Orioles +170 Minnesota Twins -190 Total: 9

The Orioles have been playing poorly, losing 9 of their last ten heading into Tuesday night. Jorge Lopez will be starting for Baltimore. He has allowed a .386 career average against this Twins lineup, with 4 home runs in 49 at bats. Minnesota ranks 5th in the majors with 21 home runs over the last 15 days. Michael Pineda will start for the Twins; he has pitched well to start the season, with a 1.01 whip and 3.9 K/BB ratio.

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Pick: Minnesota Twins -1.5

St. Louis Cardinals +157 Chicago White Sox -172 Total: 8.5

The White Sox are 0-2 in Rodon’s last two starts, but he pitched well in the most recent loss against the Yankees. This will be the first time he has faced most of this Cardinals lineup, so he should have the edge in that matchup. St. Louis is hitting just .220 over the last 15 days but will have the reliable righty John Gant on the mound. He has a miniscule 1.42 ERA on the road this year. Expect a pitcher’s duel in this one.

Pick: Under 8.5

Seattle Mariners Oakland Athletics Total:

Will update when starter for Seattle and Odds are updated.


Texas Rangers Los Angeles Angels Total:

The Rangers Dane Dunning is 0-2 in 4 road starts with a 6.06 ERA through 16.1 innings. Los Angeles starter Griffin Canning has also struggled of late. The Angels have lost their last 2 games he started and Canning has allowed 6 runs on 9 hits over 8 innings. Both bullpens rank in the bottom half of the MLB in ERA (Texas 4.07, Los Angeles 4.96), so there should be some scoring in this game.

Pick: Over

Chicago Cubs -140 Pittsburgh Pirates +130 Total: 8.5

The Pirates are banged up, with multiple key guys out with injuries. They have lost 4 of their last 5 while allowing 9 runs per game. The Cubs on the other hand rank 4th in the MLB with a .256 average over the last 30 days. Their bullpen also ranks 4th with a 3.02 ERA this season. Back the trend and take Chicago.

Pick: Chicago Cubs -140

Philadelphia Phillies Miami Marlins Total:

Will update when Miami starter and odds are released.


Cincinnati Reds +115 Washington Nationals -125 Total: 9.5

The Nationals are heating up, ranking second in the majors with a .284 average and 9th with 67 runs over the last 2 weeks. The Reds have lost 7 of their last 10, but are still averaging 4.5 runs per game. Washington’s Joe Ross has allowed at least two runs over his last 4 starts and has an 11.17 ERA at home this year.

Pick: Over 9.5

Toronto Blue +150 Jays New York Yankees -160 Total: 9

The Yankees have won 8 of their last 10 games, allowing just 3 runs per game over that span. The Blue Jays own a 4-2 series lead but will be without George Springer and Cavan Biggio in this one. Alek Manoah will make his first career appearance on Wednesday and will face a potent Yankees lineup. Domingo German has been solid for the Yankees, and they are 5-0 in his last 5 starts. Back New York.

Pick: New York Yankees -160

Atlanta Braves -105 Boston Red Sox -105 Total: 9.5

Both teams have been swinging the bat well, and rank in the top 5 in home runs over the last 15 days. The Red Sox should have the edge on the mound, however. Boston is 8-1 in Nick Pivetta’s starts this season, and their bullpen ranks 10th with a 3.67 ERA this season. They should be able to limit a Braves lineup who benefited from facing a subpar Pirates staff in their last series.

Pick: Boston Red Sox -105

Cleveland Indians Detroit Tigers Total:

Will update when Cleveland starter and odds are released.


Colorado Rockies +115 New York Mets -125 Total: 6.5

The Mets’ Marcus Stroman has a 2.75 ERA to start the year and has limited this Rockies lineup to a career .099 batting average against. New York’s bullpen has a 3.62 ERA, compared to Colorado’s 5.48 in 2021. The Rockies’ German Marquez is 0-3 and has allowed 25 baserunners through 15.2 innings on the road.  

Pick: New York Mets -125

Kansas City Royals +175 Tampa Bay Rays -195 Total: 7

The Royals’ Mike Minor has allowed 18 runs over his last 5 starts (27.1 innings) and will face a Rays lineup that ranks second with 25 home runs off lefties over the last 2 weeks. Tampa Bay’s Tyler Glasnow is 2-1 with a 2.20 ERA at home, with 44 strikeouts in 28.2 innings pitched. He has allowed just 7 hits with 11 strikeouts in 36 at bats against this Royals lineup in his career. Back the home team.

Pick: Tampa Bay Rays -1.5

Los Angeles Dodgers -130 Houston Astros +120 Total: 8.5

Los Angeles’s Trevor Bauer ranks third in the majors with 88 strikeouts and a 0.77 WHIP to start the season. The Astro’s Luis Garcia has also been effective, boasting a 2.53 ERA at home with 25 strikeouts in 21.1 innings. Dodgers are averaging 7.3 runs per game over the last two weeks, and Astros are averaging 6 per game, but I expect the pitchers to win the battle today and keep this one under.

Pick: Under 8.5

San Diego Padres -130 Milwaukee Brewers +120 Total:

The Brewers have controlled this series so far, winning the first 4 heading into Tuesday’s action. However, if recent trends hold the Padres should have the edge on the mound. The Brewes’ Adrian Houser has allowed 14 runs in his last 19 innings (4 starts), while San Diego’s Chris Paddack is 3-0 in his last 3 starts with 2 runs over 13 innings. Milwaukee also ranks 9th in the majors with a .201 average over the last 2 weeks.

Pick: San Diego Padres -130

San Francisco Giants -130 Arizona Diamondbacks +120 Total: 8.5

Arizona has been struggling from the plate, ranking 27th with a .199 average and .621 OPS over the last week. San Francisco on the other hand has averaged 6.4 runs per game over that timeframe. The Giant’s Johnny Cueto has limited the Diamondbacks lineup to a .189 career average with 18 strikeouts in 58 at bats.

Pick: San Francisco Giants -130


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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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