Wyoming vs Central Michigan Prediction 9/19/2026 Today’s College Football Picks

In this article we will formulate a Wyoming vs Central Michigan prediction for this College Football game on Saturday, September 19th at Kelly/Shorts Stadium in Mount Pleasant, Michigan. Let’s take a look at the prediction for this Week 3 matchup. 

Wyoming Cowboys Betting Preview

The Wyoming Cowboys are 1-1 this season after they defeated Northern Colorado by a score of 21-13 last week. Wyoming trailed 10-7 at halftime and 13-7 after three quarters, but they scored 14 points in the last four minutes to escape with the win. The Cowboys were out gained by a total of 345-304, went 5-12 on third downs, and tied the turnover battle at two in the game. Tyler Hughes threw for 149 yards and two touchdowns, while Jake Wilson caught three passes for 35 yards. Markell Holman rushed 11 times for 80 yards in the win. 

Prior to that game, Wyoming lost to Colorado State by a score of 35-13 in week one. The Cowboys have scored 17.0 points per game with 139.5 passing yards and 149.0 rushing yards per game, while they have allowed 24.0 points against per game this season. Tyler Hughes has thrown for 279 yards, two touchdowns, and three interceptions, while Samuel Harris has rushed 27 times for 111 yards and one score this season. 

Central Michigan Chippewas Betting Preview

The Central Michigan Chippewas are 1-1 this year after they defeated Colgate by a score of 13-10 in week two. Central Michigan trailed 10-0 at halftime and 10-6 in the fourth, but they scored the only touchdown in the fourth quarter for the win. The Chippewas out gained Colgate by a total of 276-219, went 6-16 on third downs, and won the turnover battle by a total of 4-3 in the game. Angel Flores threw for 57 yards and one interception, while Vaughn Blue caught three passes for 29 yards. Flores also led the rushing attack with 22 carries for 122 yards and one score in the win. 

Prior to that game, Central Michigan lost to New Mexico by a score of 38-7 in week one. The Chippewas have scored 10.0 points per game with 53.0 passing yards and 159.5 rushing yards per game, while they have allowed 24.0 points against per game this season. Angel Flores has thrown for 71 yards, zero touchdowns, and two interceptions, while also rushing 32 times for 149 yards and one touchdown this year. 

Why the Central Michigan Chippewas will win

• Central Michigan has won each of its last eight September games at Kramer/Deromedi Field at Kelly/Shorts Stadium.
• Wyoming has lost each of its last six road games against non-AP-ranked teams.
• Wyoming has failed to cover the spread in each of its last six games against non-AP-ranked teams.
• Central Michigan has covered the spread in seven of its last nine games at Kramer/Deromedi Field at Kelly/Shorts Stadium.
• Central Michigan has won the first half in six of its last seven games at Kramer/Deromedi Field at Kelly/Shorts Stadium.

Why the Wyoming Cowboys will win

• Wyoming has won 17 of its last 18 September games as a favorite against non-AP-ranked teams.
• Central Michigan has lost 12 of its last 13 September games as an underdog against non-AP-ranked teams.
• Central Michigan has failed to cover the spread in each of its last four games against non-AP-ranked teams.
• The favorite has covered the spread in five of Central Michigan’s last six games at Kramer/Deromedi Field at Kelly/Shorts Stadium.

Total Points Facts

• Seven of Wyoming’s last eight games as a favorite have gone UNDER the total points line.
• Each of Central Michigan’s last five games against non-AP-ranked teams have gone UNDER the total points line.

Central Michigan Chippewas Player Prop Facts

• Heading into Week 3, Angel Flores ranks 3rd in the Mid-American Conference for rushing yards (149) this season.

Wyoming Cowboys Player Prop Facts

• Heading into Week 3, Jones Thomas ranks T5th amongst FBS players for interceptions (2) this season.

Matchup/League Facts

• Central Michigan ranks 137th among FBS teams for yards per game this season (212.5).
• Central Michigan ranks 137th among FBS teams for passing yards per game this season (53.0).
• Wyoming ranks T133rd among FBS teams for H1 points per game this season (6.5).
• Wyoming ranks T129th among FBS teams for 3rd down conversion percentage this season (25.0).

Wyoming vs Central Michigan Prediction 

Central Michigan looked awful in their week one loss and they almost lost to a FCS team in week two, so they need to figure things out quickly. The Chippewas have a strong rushing attack, but their passing game is nonexistent. Wyoming also played poorly in week one and escaped against a FCS team in week two, so we have two teams struggling here. I don’t expect many points in this one, but I will take CMU at home, as their rushing attack will be the difference.

David Racey's Pick: Central Michigan ML