| MATCHUP | Wake Forest Demon Deacons | Louisville Cardinals |
|---|---|---|
| Team Records | 2-1 | 2-1 |
| Spread | +13.5 -108 | -13.5 -112 |
| Moneyline | +410 | -550 |
| Total | Over 57.5 (-108) | Under 57.5 (-112) |
| Where | L&N Federal Credit Union Stadium, Louisville, KY | |
| When | Saturday, September 26, 2026 | |
| Time | 12:00 PM EDT | |
| TV | ESPN | |
Wake Forest Demon Deacons Betting Preview
The Wake Forest Demon Deacons enter Saturday afternoon’s matchup with a 2-1 overall win-loss record (1-0 mark on the road), including victories over Akron and the Purdue Boilermakers, while losing to the Miami Hurricanes 33-20 at home last week.The Wake Forest offense has been productive through three games played in 2026. The Demon Deacons are averaging 32 points per game (42nd in nation) while producing 434.7 total yards per contest. Wake Forest has accumulated 297.7 passing yards and 137 rushing yards per game.
Turning our attention to the defensive side of the football, Wake Forest has allowed 28.3 points per game (82nd in FBS) while surrendering 379.3 total yards per contest. Looking closer at the data just presented, the Demon Deacons have allowed 235 passing yards and 144.3 rushing yards per game.
Through three games played in 2026, quarterback Gio Lopez has compiled 887 passing yards and seven passing touchdowns. Junior running back Ty Clark III has amassed 144 rushing yards and one rushing touchdown. Talented wide receiver Carlos Hernandez has been a major contributor in the receiving department, accumulating 21 receptions, 322 receiving yards and two receiving touchdowns.
Louisville Cardinals Betting Preview
The Louisville Cardinals enter Saturday afternoon’s contest with a 2-1 record (2-0 mark at home) after posting consecutive victories over Villanova and the SMU Mustangs, while losing the team’s season opener to the Ole Miss Rebels.The Louisville offense has been explosive in 2026. Let’s dive into the Louisville Cardinals relevant team data to better shed light on my previous statement. The Cardinals are averaging a massive 46 points per game while generating 515.3 total yards per contest, including 286.3 passing yards and 229 rushing yards per game, showcasing the team’s focus on a balanced offense.
Defensively, Louisville has allowed 28.3 points per game through three contests. The Cardinals are surrendering 245.3 passing yards and 161.3 rushing yards per game this season.
Quarterback Lincoln Kienholz has played exceptional football in three games played in 2026, accumulating 816 passing yards, six passing touchdowns, 154 rushing yards and four rushing touchdowns. Running back Keyjuan Brown has compiled 231 rushing yards and two rushing touchdowns. Wide receiver Tre Richardson has added 15 receptions and 243 receiving yards. Wide receiver Lawayne McCoy has also been a major contributor, amassing three receiving touchdowns this season.
Why the Wake Forest Demon Deacons will win.
• Quarterback play. Gio Lopez has thrown for 887 yards and seven passing touchdowns.• Offensive potential. Wake Forest is averaging 32 points per contest which ranks 42nd in the nation.
Why the Louisville Cardinals will win.
• Offensive firepower. The Louisville Cardinals are averaging a robust 46 points per game this season.• Offensive balance. The Cardinals are averaging 286.3 passing yards and 229 rushing yards per game.
• Home field advantage. Louisville will play in front of the team’s home crowd at L&N Federal Credit Union Stadium.
• Quarterback play. Lincoln Kienholz has compiled 816 yards, 6 touchdowns, 154 rushing yards and 4 rushing touchdowns.