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Virginia Tech vs Clemson Prediction 10/24/2026 Today’s College Football Picks

Adult, Female, Person

Jasen Vinlove-USA TODAY Sports

Virginia Tech vs Clemson Odds and Matchup Info
MATCHUP Virginia Tech Hokies Clemson Tigers
Team Records 5-2 4-2
Spread +2.5 100 -2.5 -120
Moneyline +120 -142
Total Over 49.5 (-110) Under 49.5 (-110)
Where Memorial Stadium (Clemson, SC), Clemson, SC
When Saturday, October 24, 2026
Time 07:00 PM EDT
TV ESPN

The Virginia Tech Hokies and the Clemson Tigers meet Saturday in college football action from Clemson Memorial Stadium. Here’s a Virginia Tech vs Clemson prediction. We will look at this from a betting perspective and determine the best Virginia Tech vs Clemson pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Virginia Tech Hokies Betting Preview

This year the Hokies opened things up with a nice win streak. Virginia Tech beat VMI by 70 points in the opener then kept it going with wins over Old Dominion, Maryland and Boston College from there. The next pair of outings were both losses though, as the Hokies fell to Pittsburgh and California in one-score outings for a 4-2 start to the season.

In the Georgia Tech game, the Hokies were very busy in the first half on the scoreboard. Virginia Tech ended up with a 24-3 halftime lead, then added another 10 points from there on the way to a 34-24 win. QB Ethan Grunkmeyer was 15-of-22 for 250 yards and three touchdowns. Jeffrey Overton added 14 carries for 85 yards in the winning effort.

Clemson Tigers Betting Preview

Over on the Clemson side, they had a tough draw in their opener versus LSU and predictably fell big 51-10 in a road matchup. The Tigers were able to recover in the next three games, though. Those were all wins over Georgia Southern, North Carolina and California in succession. Game five was another loss to Miami though, giving the team a 3-2 record.

Matched up against Charleston Southern last weekend the Tigers didn’t have too many issues. Clemson was up 34-0 by the end of the first half. After putting it in cruise control the rest of the way, the Tigers ended up with a 37-0 blowout/shutout win at home. QB Tait Reynolds was 17-of-26 for 127 yards and Gideon Davidson carried 13 times for 59 yards and a TD.

Virginia Tech Hokies @ Clemson Tigers Betting Trends: Week 8

 

Clemson Tigers Player Prop Facts

Virginia Tech Hokies Player Prop Facts

Matchup/League Facts

Virginia Tech vs Clemson Prediction

I’ll lean toward Virginia Tech but I could go either way here. The Hokies were able to get past Georgia Tech last weekend on 409 total yards, 19 first downs and a shaky 4-of-13 on third downs. Defensively Virginia Tech gave up 428 yards, 335 passing yards and 21 first downs but did pretty well on thirds (4-of-11) and had two takeaways. It was a solid outing for Virginia Tech after consecutive losses to Pitt and California.

As for Clemson, they held an overmatched Charleston Southern team to just six first downs, 76 total yards and 0-of-11 on third-down tries. The Tigers put up 438 yards on the other side with 231 rush yards and 28 first downs. Clemson has 22 or more points in each of their four wins and 13 or fewer in the two losses.

Andrew Jett's Pick: Virginia Tech Hokies +2.5

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