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UCLA vs Oregon Prediction 10/10/2026 Today’s College Football Picks

Sep 26, 2026; Los Angeles, California, USA;  Oregon Ducks running back Jordon Davison (0) runs against the USC Trojans defense during the first half at United Airlines Field at Los Angeles Memorial Coliseum.  Mandatory Credit: Kiyoshi Mio-Imagn Images

Sep 26, 2026; Los Angeles, California, USA; Oregon Ducks running back Jordon Davison (0) runs against the USC Trojans defense during the first half at United Airlines Field at Los Angeles Memorial Coliseum. Mandatory Credit: Kiyoshi Mio-Imagn Images

MATCHUP UCLA Bruins Oregon Ducks
Team Records 4-0 3-1
Spread +11.5 -110 -11.5 -110
Moneyline +350 -455
Total Over 59.5 (-108) Under 59.5 (-112)
Where Autzen Stadium, Eugene, OR
When Saturday, October 10, 2026
Time 03:30 PM EDT
TV CBS
The UCLA Bruins and Oregon Ducks meet Saturday in week 6 college football action at Autzen Stadium. Here’s a UCLA vs. Oregon Prediction. This article will include a UCLA vs. Oregon Pick.

UCLA Bruins Betting Preview


The UCLA Bruins beat Maryland and Purdue, and they play Wisconsin next. UCLA looks for its first 5-0 start since the 2022 season. Nico Iamaleava is completing 62.6 percent of his passes for 820 yards, 4 touchdowns, and 2 interceptions. Semaj Morgan and Brian Rowe Jr. have combined for 337 receiving yards and 2 touchdowns, while Mikey Matthews has 4 receptions.

The UCLA Bruins’ ground game is averaging 281.5 yards per contest, and Wayne Knight leads the way with 445 yards and 9 touchdowns. Defensively, UCLA is allowing 18.8 points and 317 yards per game. Sammy Omosigho leads the UCLA Bruins with 38 tackles, Sahir West has 2 sacks, and Ta’Shawn James has 3 interceptions.

Oregon Ducks Betting Preview


The Oregon Ducks beat Portland State and USC, and they play Nebraska next. Oregon has won 11 of its last 13 games. Dante Moore is completing 69.7 percent of his passes for 926 yards, 9 touchdowns, and 0 interceptions. Evan Stewart and Dakorien Moore have combined for 512 receiving yards and 7 touchdowns, while Jamari Johnson has 11 receptions.

The Oregon Ducks’ ground game is averaging 159 yards per contest, and Jordon Davison leads the way with 260 yards and 5 touchdowns. Defensively, Oregon is allowing 23.3 points and 344.3 yards per game. Koi Perich leads the Oregon Ducks with 24 tackles, Matayo Uiagalelei has 3 sacks, and Jett Washington has 2 interceptions.

Why the Oregon Ducks will win

Why the UCLA Bruins will win

Total Points Facts

Oregon Ducks Player Prop Facts

UCLA Bruins Player Prop Facts

Matchup/League Facts

UCLA vs Oregon Prediction


Oregon is going to get the benefit of the doubt because it’s at home, but this is a lot of points to give a UCLA team that’s top-10 in scoring offense. UCLA has also improved greatly on the defensive side. Oregon is still down its starting quarterback, and if the game gets tight late, I’m interested to see how the Ducks will hold up. This is one of the better UCLA teams we’ve seen in recent memory, and the offensive horses are there to give the Ducks a fight. Give me the points.

Randy Chambers's Pick: UCLA +11.5

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