Southern Mississippi vs Tulane Prediction 9/26/2026 Today’s College Football Picks
Chris Ruffolo
Sep 19, 2026; Manhattan, Kansas, USA; Tulane Green Wave quarterback Kadin Semonza (3) is forced out of the pocket by Kansas State Wildcats defensive end Wendell Gregory (1) during the first quarter at Bill Snyder Family Football Stadium. Mandatory Credit: Scott Sewell-Imagn Images
MATCHUP
Southern Mississippi Golden Eagles
Tulane Green Wave
Team Records
1-2
1-2
Spread
+17.5 -110
-17.5 -110
Moneyline
+675
-1050
Total
Over 52.5 (-108)
Under 52.5 (-112)
Where
Yulman Stadium, New Orleans, LA
When
Saturday, September 26, 2026
Time
07:00 PM EDT
TV
ESPN+
The Southern Miss Golden Eagles and the Tulane Green Wave meet in week 4 college football action from Yulman Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Southern Miss Golden Eagles vs. Tulane Green Wave Prediction.
Southern Miss Golden Eagles Recap
The Southern Miss Golden Eagles come into this game looking to bounce back from a 48-20 loss at the hands of UConn last time out to sit at 1-2 this season. After this game, Southern Miss will head on the road for a game against Troy.
Golden Eagles Drop Back-To-Back Games
Ethan Hampton has thrown for 419 yards, 2 touchdowns and 4 interceptions on 60.0% passing while Steven Robinson leads Southern Miss in rushing with 246 rushing yards and 4 touchdowns so far this season. Jamarion Wilder sits behind Robinson on the ground with 120 yards and 0 TDs. Mario Sanders leads the Golden Eagles in receiving with 233 yards on 16 catches along with 1 touchdown, while M.J. Johnson trails with 103 yards on 7 catches. On defense, Mathiu Haygood has a team-high 23 total tackles, while A.J. Thomas leads the unit with 1 sack, and Kobi Albert leads the team with 3 interceptions. Southern Miss’s defense as a whole has combined for 3 sacks and 5 interceptions so far this season.
Tulane Green Wave Recap
The Tulane Green Wave come into this game looking to bounce back from a 31-20 loss at the hands of Kansas State last time out to sit at 1-2 this season. After this game, Tulane will head on the road for a game against Army.
Green Wave Looking For Consistency
Kadin Semonza has thrown for 517 yards, 1 touchdown and 0 interceptions on 55.1% passing while Jaylin Lucas leads Tulane in rushing with 215 rushing yards and 1 touchdown so far this season. Johnnie Daniels sits behind Lucas on the ground with 98 yards and 2 TDs. Destyn Hill leads the Green Wave in receiving with 158 yards on 9 catches along with 1 touchdown, while Bredoell Richardson trails with 82 yards on 6 catches. On defense, Kevin Adams II has a team-high 29 total tackles (10 solo, 19 assisted), while Makai Williams leads the unit with 1 sack. Tulane’s defense as a whole has combined for 2 sacks and 0 interceptions so far this season.
Southern Miss Golden Eagles @ Tulane Green Wave Betting Trends: Week 4
Why the Tulane Green Wave will win
Tulane has won 20 of its last 21 games against non-AP-ranked teams at Yulman Stadium.
Southern Miss has lost each of its last nine games as a road underdog.
Southern Miss has failed to cover the spread in eight of its last nine September games as an underdog.
Tulane has covered the spread in four of its last five home games against non-conference opponents.
Southern Miss has lost the first half in each of its last 11 road games against non-conference opponents.
Tulane has won the first quarter in eight of its last nine September home games against non-AP-ranked teams.
Why the Southern Miss Golden Eagles will win
Tulane has lost four of its last five games against non-conference opponents.
The road team has won each of the last three games between Southern Miss and Tulane.
Tulane has failed to cover the spread in each of its last five games as a home favorite.
The underdog has covered the spread in each of Tulane’s last five games at Yulman Stadium.
Tulane has lost the first half in four of its last five games against non-conference opponents.
Total Points Facts
Each of Tulane’s last four games against teams from Mississippi have gone UNDER the total points line.
Five of Southern Miss’ last six games as an underdog in Louisiana have gone OVER the total points line.
Tulane Green Wave Player Prop Facts
Heading into Week 4, Tavare Smith ranks 4th in the American Conference for kick return yards (92) this season.
Southern Miss Golden Eagles Player Prop Facts
Heading into Week 4, Ja’Kobi Albert ranks T2nd amongst FBS players for interceptions (3) this season.
Matchup/League Facts
Tulane ranks 138th among FBS teams for time of possession per game this season (24:01).
Tulane ranks T1st among FBS teams for red zone percentage this season (100.0).
Southern Miss ranks T132nd among FBS teams for Q1 opponent points per game this season (11.3).
Southern Miss ranks 131st among FBS teams for rushing yards allowed per game this season (220.0).
Southern Miss Golden Eagles vs. Tulane Green Wave Prediction
I’m on the Golden Eagles and the points in this one. This is just too much to give up with Tulane in this spot in my opinion, as the Green Wave are the better team but not by enough to warrant laying almost 3 TDs with them. I think Southern Miss will try to ugly this game up and make it a rock fight. Give me the points with the Golden Eagles in this one.
