| MATCHUP | Ohio State Buckeyes | Indiana Hoosiers |
|---|---|---|
| Team Records | 5-1 | 6-0 |
| Spread | -3.5 -108 | +3.5 -112 |
| Moneyline | -180 | +150 |
| Total | Over 50.5 (-118) | Under 50.5 (-102) |
| Where | Memorial Stadium (Bloomington, IN), Bloomington, IN | |
| When | Saturday, October 17, 2026 | |
| Time | 12:00 PM EDT | |
| TV | Fox | |
In this article, we will formulate an Ohio State vs Indiana Prediction for this College Football Week 7 matchup on Saturday, October 17th. Let’s take a look at the prediction for this College Football matchup.
Indiana Hoosiers Preview
Indiana has a 6-0 record and a 3-0 record in the Big Ten. They are coming off a 20-17 road win against Nebraska and will face Michigan and Minnesota next.
Offensively, Indiana averages 40.2 points per game, ranking 14th in the nation, while defensively, they allow 11.8 points per game, which is 5th. Indiana averages 462.7 total yards per game (241.3 passing and 221.3 rushing), while allowing 263.5 total yards per game (75 rushing and 188.5 passing).
Josh Hoover leads Indiana with 1,364 passing yards with 68.2% completed passes and 17 touchdowns. Turbo Richard leads the team in rushing yards with 597, while Charlie Becker has a team-high 529 receiving yards and 30 receptions. Defensively, Isaiah Jones has a team-high 46 total tackles (28 of them solo), while Tobi Osunsanmi leads the team with 5 sacks.
Ohio State Buckeyes Preview
Ohio State has a 5-1 record and a 3-0 record in the Big Ten. They are coming off a 45-16 home win against Maryland and will face USC and Oregon next.
Offensively, Ohio State averages 42.7 points per game, ranking 7th in the nation, while defensively, they allow 13.2 points per game, which is 8th. Ohio State averages 503.5 total yards per game (337.8 passing and 165.7 rushing), while allowing 246.8 total yards per game (96.2 rushing and 150.7 passing).
Julian Sayin leads Ohio State with 1,772 passing yards with 71.2% completed passes and 17 touchdowns. Bo Jackson leads the team in rushing yards with 460, while Jeremiah Smith has a team-high 916 receiving yards and 48 receptions. Defensively, Payton Pierce and Earl Little lead the team with 30 total tackles each, while Kenyatta Jackson leads the team with 3 sacks.
Ohio State Buckeyes @ Indiana Hoosiers Betting Trends: Week 7
Why the Indiana Hoosiers will win
- Indiana has won each of its last 22 games.
- Ohio State has lost three of its last four games against AP-ranked teams.
- The underdog has covered the spread in six of Indiana’s last seven games.
- The team ranked 4th in the AP Poll has failed to cover the spread in 16 of its last 20 games.
- Indiana has won the first quarter in each of its last nine games against conference opponents at Memorial Stadium (Bloomington).
- Indiana has won the first half in each of its last 19 games at Memorial Stadium (Bloomington).
Why the Ohio State Buckeyes will win
- Ohio State has won 24 of its last 25 games in October.
- Indiana has lost 15 of its last 17 games against teams from Ohio.
- Ohio State has covered the spread in seven of its last eight games against top-5 AP-ranked teams.
- Indiana has failed to cover the spread in each of its last five games at Memorial Stadium (Bloomington).
- Ohio State has won the first half in each of its last 14 games against conference opponents.
- Ohio State has won the first quarter in each of its last 12 road games in October.
Total Points Facts
- Each of Ohio State’s last seven road games have gone UNDER the total points line.
- Six of Indiana’s last seven games against teams with an AP Ranking of 4 have gone UNDER the total points line.
Indiana Hoosiers Player Prop Facts
- Josh Hoover has thrown zero interceptions in seven consecutive games – equal-longest streak in the FBS, heading into Week 7.
Ohio State Buckeyes Player Prop Facts
- Jeremiah Smith has recorded 75+ receiving yards in eight consecutive games – longest streak in the FBS, heading into Week 7.
Matchup/League Facts
- Indiana has recorded the equal-most home wins by a margin of 30+ points of any FBS team this season (3).
- Indiana has recorded the equal-most home wins by a margin of 35+ points of any FBS team this season (3).
- Ohio State has recorded the equal-most home wins by a margin of 10+ points of any FBS team this season (4).
- Ohio State has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (4).
Ohio State vs Indiana Prediction
In this Ohio State vs Indiana prediction, Ohio State is coming as -3.5 road favorites. Both teams have been exclellent this season, as Indiana has been undefeated and Ohio State has lost only once, but Indiana is a measly 1-5 against the spread and its 5th-best defense has been much weaker as of late, allowing 18.3 points per game in its last three games. On the flip side, Ohio State’s offense has been scorching-hot and I expect them to get the job done on the road in this one. Take Ohio State and lay the -3.5 points.