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North Carolina vs Clemson Prediction 9/19/2026 Today’s College Football Picks

Sep 12, 2026; Chapel Hill, North Carolina, USA; North Carolina Tar Heels quarterback Billy Edwards Jr. (9) looks to pass in the first quarter at Kenan Stadium. Mandatory Credit: Bob Donnan-Imagn Images

Sep 12, 2026; Chapel Hill, North Carolina, USA; North Carolina Tar Heels quarterback Billy Edwards Jr. (9) looks to pass in the first quarter at Kenan Stadium. Mandatory Credit: Bob Donnan-Imagn Images

MATCHUP North Carolina Tar Heels Clemson Tigers
Team Records 2-0 1-1
Spread +3 -105 -3 -115
Moneyline +140 -166
Total Over 43.5 (-115) Under 43.5 (-105)
Where Memorial Stadium (Clemson, SC), Clemson, SC
When Saturday, September 19, 2026
Time 12:00 PM EDT
TV ESPN
The UNC Tar Heels and the Clemson Tigers meet in week 3 college football action from Memorial Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a UNC Tar Heels vs. Clemson Tigers Prediction.

UNC Tar Heels Recap

The UNC Tar Heels come into this game looking to add on to their 35-3 win over East Tennessee State last time out to sit at 2-0 on the year. After this game, UNC will head home for a game against Notre Dame.

Tar Heels Looking To Stay Unbeaten

Billy Edwards Jr. has thrown for 476 yards, 2 touchdowns and 0 interceptions on 64.6% passing while Benjamin Hall leads the Tar Heels in rushing with 85 rushing yards and 0 touchdowns so far this season. Zero more Tar Heels have at least 100 rushing yards as well this season including Jaylen McGill who has 73 yards and 1 TD while Jelani Thurman leads North Carolina in receiving with 165 receiving yards and 8 catches along with 1 touchdown so far this season. On defense, Derek McDonald has a team-high 14 total tackles while Xavier Lewis leads the team with 4 sacks, and North Carolina’s defense as a whole has combined for 7 sacks and 1 interception so far this season.

Clemson Tigers Recap

The Clemson Tigers come into this game looking to add on to their 22-7 win over Georgia Southern last time out to improve to 1-1 on the year. After this game, Clemson will head on the road for a game against Cal.

Tigers Looking To Build On First Win

Tait Reynolds has thrown for 200 yards, 0 touchdowns and 0 interceptions on 60.6% passing while Gideon Davidson leads the Tigers in rushing with 82 rushing yards and 0 touchdowns so far this season. Zero more Tigers have at least 100 rushing yards as well this season including Chris Johnson Jr. who has 53 yards and 0 TDs while T.J. Moore leads Clemson in receiving with 134 receiving yards and 11 catches along with 1 touchdown so far this season. On defense, Corey Myrick and Sammy Brown are tied with a team-high 16 total tackles each while Will Heldt leads the team with 2 sacks, and Clemson’s defense as a whole has combined for 3 sacks and 1 interception so far this season.

North Carolina Tar Heels @ Clemson Tigers Betting Trends: Week 3


Why the Clemson Tigers will win

Why the North Carolina Tar Heels will win

Total Points Facts

Clemson Tigers Player Prop Facts

North Carolina Tar Heels Player Prop Facts

Matchup/League Facts

UNC Tar Heels vs. Clemson Tigers Prediction

I’m on UNC and the points in this one. I just think that Clemson’s time has passed and this might be the worst team that Dabo Swinney has had in his time as Clemson’s head coach. I think the Tigers just fall flat once again as the name brand respect of Clemson continues to linger and make this team overvalued, even in a pick ‘em. Give me UNC.

Chris Ruffolo's Pick: North Carolina +3

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