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Louisiana vs Charlotte Prediction 9/26/2026 Today’s College Football Picks

Sep 12, 2026; Los Angeles, California, USA; Louisiana Ragin' Cajuns quarterback Lunch Winfield (7) throws the ball against the Southern California Trojans in the second half at United Airlines Field at Los Angeles Memorial Coliseum. Mandatory Credit: Kirby Lee-Imagn Images

Sep 12, 2026; Los Angeles, California, USA; Louisiana Ragin' Cajuns quarterback Lunch Winfield (7) throws the ball against the Southern California Trojans in the second half at United Airlines Field at Los Angeles Memorial Coliseum. Mandatory Credit: Kirby Lee-Imagn Images

MATCHUP Louisiana Ragin' Cajuns Charlotte 49ers
Team Records 2-1 0-3
Spread -10 -110 +10 -110
Moneyline -410 +320
Total Over 48.5 (-112) Under 48.5 (-108)
Where Jerry Richardson Stadium, Charlotte, NC
When Saturday, September 26, 2026
Time 06:30 PM EDT
TV ESPN+
In this article we will formulate a Louisiana vs Charlotte prediction for this College Football game on Saturday, September 26th at Jerry Richardson Stadium in Charlotte, North Carolina. Let’s take a look at the prediction for this Week 4 matchup. 

Louisiana Ragin’ Cajuns Betting Preview

The Louisiana Ragin’ Cajuns are 2-1 this year after they defeated UAB by a score of 21-14 last week. Louisiana led 21-7 at halftime and they were able to get the win, but they failed to score in the second half. The Ragin’ Cajuns out gained UAB by a total of 335-218, went 6-16 on third downs, and lost the turnover battle by a total of 2-1 in the game. Lunch Winfield threw for 110 yards, while Landon Strother caught five passes for 41 yards. Winfield also led the rushing attack with 91 yards and two scores on 19 carries in the game. 

Prior to that win, Louisiana lost to USC by a score of 49-30, but did defeat Lamar by a score of 38-7 before that. The Ragin’ Cajuns have scored 29.7 points per game with 184.3 passing yards and 204.7 rushing yards per game, while they have allowed 23.3 points against per game this season. Lunch Winfield has thrown for 511 yards with one touchdown and two interceptions, while also rushing for 267 yards and five scores this year. 

Charlotte 49ers Betting Preview

The Charlotte 49ers are 0-3 this season after they lost to App State by a score of 26-21 in their last game. Charlotte trailed 13-7 at halftime and they allowed the first 13 points of the second half, before falling short in their comeback attempt. The 49ers were out gained by a total of 435-247, went 1-10 on third downs, and tied the turnover battle at two in the game. Cole Gonzales threw for 211 yards and two interceptions, while Jaden Barnes caught 10 passes for 97 yards. Henry Rutledge rushed seven times for 29 yards in the loss. 

Prior to that game, Charlotte lost to Ole Miss by a score of 41-9 and The Citadel by a score of 43-41. The 49ers have scored 23.7 points per game with 237.3 passing yards and 131.7 rushing yards per game, while they have allowed 36.7 points against per game this season. Cole Gonzales has thrown for 661 yards with three touchdowns and five interceptions, while Jaden Barnes has 21 receptions for 207 yards this season. 

Why the Charlotte 49ers will win

Why the Louisiana Ragin’ Cajuns will win

Total Points Facts

Charlotte 49ers Player Prop Facts

Louisiana Ragin’ Cajuns Player Prop Facts

Matchup/League Facts

Louisiana vs Charlotte Prediction 

Charlotte comes into this matchup looking for their first win of the season and they already have a terrible loss to a FCS school in week one. The 49ers have allowed 41+ points in two of their three games, but they did play a little better last week. Louisiana is 2-1 so far, but their offense disappeared in the second half last week. The Ragin’ Cajuns don’t have a great passing game, but their QB is great at running. I don’t think we will see many points in this game, but Louisiana should be able to cover here.

David Racey's Pick: Louisiana -10

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