James Madison vs Old Dominion Prediction 9/26/2026 Today’s College Football Picks
Chris Ruffolo
Dec 17, 2025; Orlando, FL, USA; Old Dominion Monarchs quarterback Quinn Henicle (10) runs into the end-zone for a touchdown against the South Florida Bulls in the fourth quarterduring the Cure Bowl at Camping World Stadium. Mandatory Credit: Nathan Ray Seebeck-Imagn Images
MATCHUP
James Madison Dukes
Old Dominion Monarchs
Team Records
3-0
1-2
Spread
-6 -108
+6 -112
Moneyline
-225
+185
Total
Over 44.5 (-115)
Under 44.5 (-105)
Where
Old Dominion Stadium
When
Saturday, September 26, 2026
Time
06:00 PM EDT
TV
ESPN+
The James Madison Dukes and the Old Dominion Monarchs meet in week 4 college football action from S.B. Ballard Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a James Madison Dukes vs. Old Dominion Monarchs Prediction.
James Madison Dukes Recap
The James Madison Dukes come into this game looking to build on their 26-13 win over San Diego State last time out to sit at 3-0 on the year. After this game, JMU will head home for a game against Marshall.
Dukes Looking To Stay Unbeaten
Alston Maiden has thrown for 111 yards, 3 touchdowns and 0 interceptions on 87.5% passing while Nick Herman leads James Madison in rushing with 196 rushing yards and 2 touchdowns so far this season. George Pettaway sits behind Herman on the ground with 161 yards and 2 TDs. Corey Scott leads the Dukes in receiving with 128 yards on 12 catches, while Braeden Wisloski trails with 116 yards on 8 catches along with 1 touchdown. On defense, Jayson Harvey and Nakian Jackson share a team-high 27 total tackles, while Ariall Wilson leads the unit with 1 sack. JT Hester and DJ Kelly have each recorded 1 interception. James Madison’s defense as a whole has combined for 4 sacks and 2 interceptions so far this season.
Old Dominion Monarchs Recap
The Old Dominion Monarchs come into this game looking to bounce back from a 20-17 loss to East Carolina last time out to sit at 1-2 this season. After this game, Old Dominion will head on the road for a game against Georgia State.
Monarchs Drop Back-To-Back Games
Quinn Henicle has thrown for 424 yards, 3 touchdowns and 2 interceptions on 55.6% passing while also leading Old Dominion in rushing with 224 rushing yards and 4 touchdowns so far this season. Devin Roche sits behind Henicle on the ground with 192 yards and 0 TDs. Josh Rodriguez leads the Monarchs in receiving with 121 yards on 9 catches, while JJ Harrell trails with 91 yards on 7 catches. On defense, Mario Thompson has a team-high 28 total tackles, Jackson Forrest leads the unit with 3 sacks, and Mario Easterly recorded 1 interception. Old Dominion’s defense as a whole has combined for 11 sacks and 1 interception so far this season.
James Madison Dukes @ Old Dominion Monarchs Betting Trends: Week 4
Why the Old Dominion Monarchs will win
Old Dominion has won seven of its last eight home games.
Old Dominion has covered the spread in five of its last six September games as a home underdog.
Old Dominion has won the first half in seven of its last eight home games.
Old Dominion has won the first quarter in six of its last eight games as an underdog against non-AP-ranked teams.
Why the James Madison Dukes will win
James Madison has won each of its last 14 games against non-AP-ranked teams.
Old Dominion has lost 10 of its last 11 games as an underdog against teams from Virginia.
James Madison has covered the spread in each of its last eight games in September.
Old Dominion has failed to cover the spread in each of its last six home games against teams from Virginia.
James Madison has won the first half in each of its last six games against conference opponents.
James Madison has won the first quarter in eight of its last nine games against non-AP-ranked teams.
Total Points Facts
Eight of Old Dominion’s last nine games have gone UNDER the total points line.
Five of James Madison’s last six games against conference opponents have gone OVER the total points line.
Old Dominion Monarchs Player Prop Facts
Heading into Week 4, Jackson Forrest ranks T9th amongst FBS players for sacks (3.0) this season.
James Madison Dukes Player Prop Facts
Heading into Week 4, Nick Herman ranks 10th amongst qualified players for Yards Per Carry (8.5) this season.
Matchup/League Facts
Old Dominion ranks T1st among FBS teams for red zone percentage this season (100.0).
Old Dominion ranks T133rd among FBS teams for 1st downs this season (41).
James Madison ranks 137th among FBS teams for time of possession per game this season (25:11).
James Madison ranks T3rd among FBS teams for H1 opponent points per game this season (3.0).
James Madison Dukes vs. Old Dominion Monarchs Prediction
I’m on James Madison in this one. I just think this is Billy Napier’s conference in the Sun Belt, and I think this is a gift of a line here. Sure, it’s a rivalry matchup with a pair of Virginia teams, but the talent level on both sides for me is a stark difference and I think JMU runs over Old Dominion here.
