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Iowa State vs Arizona Prediction 10/24/2026 Today’s College Football Picks

Oct 10, 2026; Morgantown, West Virginia, USA; Arizona Wildcats running back Kedrick Reescano (3) warms up prior to their game against the West Virginia Mountaineers at Milan Puskar Stadium. Mandatory Credit: Ben Queen-Imagn Images

Oct 10, 2026; Morgantown, West Virginia, USA; Arizona Wildcats running back Kedrick Reescano (3) warms up prior to their game against the West Virginia Mountaineers at Milan Puskar Stadium. Mandatory Credit: Ben Queen-Imagn Images

Iowa State vs Arizona Odds and Matchup Info
MATCHUP Iowa State Cyclones Arizona Wildcats
Team Records 3-3 5-1
Spread +10 -112 -10 -108
Moneyline +250 -310
Total Over 51.5 (-102) Under 51.5 (-118)
Where Arizona Stadium, Tucson, AZ
When Saturday, October 24, 2026
Time 07:30 PM EDT
TV ESPN2

The Iowa State Cyclones and Arizona Wildcats meet Saturday in week 8 college football action at Casino Del Sol Stadium. Here’s an Iowa State vs. Arizona Prediction. This article will include an Iowa State vs. Arizona Pick.

Iowa State Cyclones Betting Preview

The Iowa State Cyclones lost to BYU, beat West Virginia, and they play Oklahoma State next. Iowa State has won 6 of its last 9 games. Jaylen Raynor is completing 57.4 percent of his passes for 1,001 yards, 7 touchdowns, and 4 interceptions. Dominic Overby and Omari Hayes have combined for 420 receiving yards and 2 touchdowns, while Cody Jackson has 10 receptions.

The Iowa State Cyclones’ ground game is averaging 181.5 yards per contest, and Aiden Flora leads the way with 680 yards and 6 touchdowns. Defensively, Iowa State is allowing 21.7 points and 352.3 yards per game. Sullivan Schlimgen leads the Iowa State Cyclones with 56 tackles, Isaac Terell has 3 sacks, and Beni Ngoyi has 1 interception.

Arizona Wildcats Betting Preview

The Arizona Wildcats beat Cincinnati and West Virginia, and play Texas Tech next. The Arizona Wildcats have won 4 straight games. Noah Fifita is completing 73.3 percent of his passes for 1,756 yards, 16 touchdowns, and 4 interceptions. Isaiah Mizell and Tre Spivey have combined for 673 receiving yards and 8 touchdowns, while Brandon Phelps has 12 receptions.

The Arizona Wildcats’ ground game is averaging 149.8 yards per contest, and Kedrick Reescano leads the way with 262 yards and 4 touchdowns. Defensively, Arizona is allowing 19 points and 330.5 yards per game. Taye Brown leads the Arizona Wildcats with 39 tackles, Chase Kennedy has 4 sacks, and Quinn Olson has 1 interception.

Why the Arizona Wildcats will win

Why the Iowa State Cyclones will win

Total Points Facts

Arizona Wildcats Player Prop Facts

Iowa State Cyclones Player Prop Facts

Matchup/League Facts

Iowa State vs Arizona Prediction

I like getting points with a team that’s had an extra week to prepare, but Iowa State can’t score the football and has been held to 17 or fewer points in 3 of its last 5 games. That’s not going to fly against a team like Arizona, who is also playing its best ball of the season right now. Arizona just went into Morgantown and dropped 52 points on West Virginia’s head. Iowa State has usually been a sneaky good team as an underdog over the years, but this feels like a bad matchup for the Cyclones, and there aren’t enough horses to keep up. I’ll lay the points with Arizona.

Randy Chambers's Pick: Arizona -10

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