Indiana vs Nebraska Prediction 10/10/2026 Today’s College Football Picks
Chris Ruffolo
Oct 3, 2026; Piscataway, New Jersey, USA; Indiana Hoosiers quarterback Grant Wilson (2) signals during the second half against the Rutgers Scarlet Knights at SHI Stadium. Mandatory Credit: Vincent Carchietta-Imagn Images
MATCHUP
Indiana Hoosiers
Nebraska Cornhuskers
Team Records
5-0
5-0
Spread
-7.5 -105
+7.5 -115
Moneyline
-305
+245
Total
Over 47.5 (-115)
Under 47.5 (-105)
Where
Memorial Stadium (Lincoln, NE), Lincoln, NE
When
Saturday, October 10, 2026
Time
12:00 PM EDT
TV
Fox
The Indiana Hoosiers and the Nebraska Cornhuskers meet in week 6 college football action from Memorial Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Indiana Hoosiers vs. Nebraska Cornhuskers Prediction.
Indiana Hoosiers Recap
The Indiana Hoosiers come into this game looking to add on to their 47-15 win over Rutgers last time out to sit at 5-0 this season. After this game, Indiana will head home for a game against Ohio State.
Hoosiers Looking To Stay Undefeated
Josh Hoover has thrown for 1,101 yards, 15 touchdowns and 0 interceptions on 71.0% passing while Turbo Richard leads Indiana in rushing with 587 yards and 5 touchdowns through 5 games this season. Lee Beebe Jr. sits behind Richard on the ground with 520 yards and 4 touchdowns. Charlie Becker leads the Hoosiers in receiving with 477 yards and 27 catches along with 8 touchdowns, while Nick Marsh trails with 341 yards and 23 catches. On defense, Isaiah Jones has a team-high 37 tackles while Indiana’s defense as a whole has combined for 15 sacks and 3 interceptions through 5 games this season.
Nebraska Cornhuskers Recap
The Nebraska Cornhuskers come into this game looking to build on their 48-23 win over Maryland last time out to sit at 5-0 this season. After this game, the Cornhuskers will head on the road for a game against Oregon.
Cornhuskers Looking For Home Upset
Anthony Colandrea has thrown for 1,142 yards, 13 touchdowns and 2 interceptions on 65.7% passing while Jamal Rule leads Nebraska in rushing with 333 yards and 5 touchdowns through 5 games this season. Mekhi Nelson sits behind Rule on the ground with 266 yards and 4 touchdowns. Kwazi Gilmer leads the Cornhuskers in receiving with 387 yards and 29 catches along with 6 touchdowns, while Jacory Barney Jr. trails with 233 yards and 18 catches. On defense, Owen Chambliss has a team-high 26 tackles while Nebraska’s defense as a whole has combined for 16 sacks and 6 interceptions through 5 games this season.
Nebraska has won each of its last six home games in October.
Indiana has failed to cover the spread in five of its last six games.
Nebraska has covered the spread in four of its last five games.
Nebraska has won the first quarter in four of its last five games in October.
Nebraska has won the first half in each of its last six home games in October.
Why the Indiana Hoosiers will win
Nebraska has lost each of its last 30 games against AP-ranked teams.
Indiana has won each of its last 26 games against non-AP-ranked teams.
Nebraska has failed to cover the spread in eight of its last nine home games against top-15 AP-ranked teams.
The favorite has covered the spread in seven of Nebraska’s last eight games.
The favorite has won the first half in each of Indiana’s last 15 games.
Indiana has won the first quarter in 15 of its last 16 games against conference opponents.
Total Points Facts
Seven of Nebraska’s last eight home games against conference opponents have gone OVER the total points line.
Seven of Indiana’s last eight October games as a favorite have gone OVER the total points line.
Nebraska Cornhuskers Player Prop Facts
Heading into Week 6, Kwazi Gilmer ranks T6th amongst FBS players for receiving touchdowns (6) this season.
Indiana Hoosiers Player Prop Facts
Heading into Week 6, Josh Hoover ranks 2nd amongst qualified players for passer rating (203.7) this season.
Matchup/League Facts
Nebraska has recorded the equal-most home wins by a margin of 10+ points of any FBS team this season (4).
Nebraska has recorded the equal-most home wins by a margin of 15+ points of any FBS team this season (4).
Indiana has recorded the equal-most home wins by a margin of 30+ points of any FBS team this season (3).
Indiana has recorded the most home wins by a margin of 35+ points of any FBS team this season (3).
Indiana Hoosiers vs. Nebraska Cornhuskers Prediction
I’m on Indiana here. I’d like to take a shot with Nebraska but they’ve been on a horrendous losing streak against ranked teams and while Indiana doesn’t feel like they have the same pop as last year’s national champion, I think there’s still enough here for Indiana to win this game by a 34-24 final, so I’ll roll with the Hoosiers in this one.
