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East Carolina vs Memphis Prediction 10/22/2026 Today’s College Football Picks

Oct. 9, 2026; Tuscaloosa, AL, USA;  Hillcrest's Jaylin Bennett (25) pushes McAdory’s Carter Feagin (4) out of bounds at Hillcrest High.

Oct. 9, 2026; Tuscaloosa, AL, USA; Hillcrest's Jaylin Bennett (25) pushes McAdory’s Carter Feagin (4) out of bounds at Hillcrest High.

East Carolina vs Memphis Odds and Matchup Info
MATCHUP East Carolina Pirates Memphis Tigers
Team Records 3-3 5-2
Spread +10.5 -112 -10.5 -108
Moneyline +330 -425
Total Over 54.5 (-108) Under 54.5 (-112)
Where Simmons Bank Liberty Stadium, Memphis, TN
When Thursday, October 22, 2026
Time 07:30 PM EDT
TV ESPN2

The East Carolina Pirates and Memphis Tigers meet Thursday in week 8 college football action at Simmons Bank Liberty Stadium. Here’s an East Carolina vs. Memphis Prediction. This article will include an East Carolina vs. Memphis Pick.

East Carolina Pirates Betting Preview

The East Carolina Pirates beat Rice, lost to UAB, and they play Temple next. East Carolina has won 3 of its last 4 games. Emory Williams is completing 65.4 percent of his passes for 655 yards, 7 touchdowns, and 2 interceptions. Ray Ray Joseph Jr. and Jeremiah Melvin have combined for 460 receiving yards and 4 touchdowns, while Jason Dickerson has 9 receptions.

The East Carolina Pirates’ ground game is averaging 155.5 yards per contest, and TJ Engleman Jr. leads the way with 490 yards and 3 touchdowns. Defensively, East Carolina is allowing 23.8 points and 326.3 yards per game. DJ Johnson Jr. leads the East Carolina Pirates with 42 tackles, Jasiyah Robinson has 2.5 sacks, and Ayden Duncanson has 2 interceptions.

Memphis Tigers Betting Preview

The Memphis Tigers beat UAB, lost to Tulane, and they play Army next. Memphis has won 3 of its last 4 games. Marcus Stokes is completing 66.9 percent of his passes for 1,841 yards, 18 touchdowns, and 6 interceptions. Hunter Tipton and Stonka Burnside have combined for 721 receiving yards and 8 touchdowns, while Jermane Hayes has 25 receptions.

The Memphis Tigers’ ground game is averaging 236.8 yards per contest, and Jaylin Carter leads the way with 780 yards and 8 touchdowns. Defensively, Memphis is allowing 22.3 points and 372.4 yards per game. Mike Montgomery leads the Memphis Tigers with 47 tackles, Elijah Kinsler has 4.5 sacks, and Dylan Smith has 3 interceptions.

Why the Memphis Tigers will win

Why the East Carolina Pirates will win

Total Points Facts

Memphis Tigers Player Prop Facts

East Carolina Pirates Player Prop Facts

Matchup/League Facts

East Carolina vs Memphis Prediction

Both teams are coming off bad losses, so it’s going to be interesting to see how both sides rebound. Memphis is the more talented side and has had better covering success, but this is a lot of points for a team that’s underachieving for the most part and can’t stop the run defensively. East Carolina is below average on both sides of the ball, but it’s a run-first offense and should be able to move the ball a bit against this Memphis front. A hook on top of a key number as well. There are better options out there on Thursday, but I’ll lean toward the points. It’s a fade of Memphis more than anything, though.

Randy Chambers's Pick: East Carolina +10.5

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