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Clemson vs Syracuse Prediction 11/7/2026 Today’s College Football Picks

Oct 31, 2026; Tallahassee, Florida, USA;  Florida State Seminoles quarterback Ashton Daniels (14) fumbles the ball during the second half against the Clemson Tigers at Doak S. Campbell Stadium.  Mandatory Credit: Melina Myers-Imagn Images

Oct 31, 2026; Tallahassee, Florida, USA; Florida State Seminoles quarterback Ashton Daniels (14) fumbles the ball during the second half against the Clemson Tigers at Doak S. Campbell Stadium. Mandatory Credit: Melina Myers-Imagn Images

Clemson vs Syracuse Odds and Matchup Info
MATCHUP Clemson Tigers Syracuse Orange
Team Records 5-3 4-4
Spread -2.5 -110 +2.5 -110
Moneyline -135 +114
Total Over 49.5 (-110) Under 49.5 (-110)
Where JMA Wireless Dome, Syracuse, NY
When Saturday, November 7, 2026
Time 12:00 PM EST
TV ESPN2

Clemson vs Syracuse Prediction


Clemson has been able to get wins here and there to prevent things from completely falling off the rails, but this is a bad team no matter how you slice it. We identified it early and haven’t made a habit of getting behind Clemson. Meanwhile, Syracuse is coming off back-to-back upset wins and has covered four straight games. A bounce here or bounce there, and Syracuse is riding four straight big underdog wins, and you’re chilling on your own private island.

Basically, what I’m saying is it feels like Clemson is still being favored off of its name, and it simply takes more than that for me. I expect Syracuse to win this game outright if we’re being honest, but I’ll grab the points just to be safe.

Clemson Tigers Betting Preview


The Clemson Tigers lost to Virginia Tech, beat Florida State, and they play Georgia Tech next. Clemson has won 5 of its last 7 games. Tait Reynolds is completing 65.1 percent of his passes for 1,285 yards, 3 touchdowns, and 3 interceptions. Bryant Wesco Jr. and Tyler Brown have combined for 743 receiving yards on 74 catches, while T.J. Moore has 33 receptions.

The Clemson Tigers’ ground game is averaging 152 yards per contest, and Gideon Davidson leads the way with 528 yards and 5 touchdowns. Defensively, Clemson is allowing 21.6 points and 329.3 yards per game. Corey Myrick leads the Clemson Tigers with 63 tackles, Will Heldt has 7 sacks, and Elliot Washington II has 5 interceptions.

Syracuse Orange Betting Preview


The Syracuse Orange beat North Carolina and SMU, and they play NC State next. Syracuse has lost 4 of its last 7 games. Steve Angeli is completing 57 percent of his passes for 1,187 yards, 7 touchdowns, and 5 interceptions. Umari Hatcher and Daunte Bacheyie have combined for 1,286 receiving yards and 12 touchdowns, while Calvin Russell III has 19 receptions.

The Syracuse Orange ground game is averaging 161.1 yards per contest, and Tylik Hill leads the way with 515 yards and 1 touchdown. Defensively, Syracuse is allowing 26.4 points and 346.9 yards per game. Chris D’Appolonia leads the Syracuse Orange with 57 tackles, Keyshawn Johnson has 6 sacks, and Davien Kerr has 3 interceptions.

Why the Syracuse Orange will win

Why the Clemson Tigers will win

Total Points Facts

Syracuse Orange Player Prop Facts

Clemson Tigers Player Prop Facts

Matchup/League Facts

Randy Chambers's Pick: Syracuse +2.5

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