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Arkansas State vs Southern Mississippi Prediction 10/17/2026 Today’s College Football Picks

Southern Miss Golden Eagles quarterback Ethan Hampton (5) looks to pass during the college football game between the Southern Miss Golden Eagles and the UConn Huskies at Carlisle-Faulkner Field at Renasant Stadium in Hattiesburg. Photo by Matt Bush.

Southern Miss Golden Eagles quarterback Ethan Hampton (5) looks to pass during the college football game between the Southern Miss Golden Eagles and the UConn Huskies at Carlisle-Faulkner Field at Renasant Stadium in Hattiesburg. Photo by Matt Bush.

MATCHUP Arkansas State Red Wolves Southern Mississippi Golden Eagles
Team Records 2-4 1-4
Spread -7 -105 +7 -115
Moneyline -265 +215
Total Over 62.5 (-110) Under 62.5 (-110)
Where M. M. Roberts Stadium, Hattiesburg, MS
When Saturday, October 17, 2026
Time 07:00 PM EDT
TV ESPN+

The Arkansas State Red Wolves and the Southern Miss Golden Eagles meet Saturday in college football action from Roberts Stadium in Hattiesburg. Here’s an Arkansas State vs Southern Miss prediction. We will look at this from a betting perspective and determine the best Arkansas State vs Southern Miss pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Arkansas State Red Wolves Betting Preview

The Red Wolves haven’t had a whole lot of luck this year so far. Arkansas State kicked off the season on a choppy run, losing to Memphis and TCU alongside wins over West Georgia and Kennesaw State across their first four outings. Since then it’s been two more losses to Louisiana and South Alabama for a 2-4 start to the year.

In the South Alabama game last Thursday the Red Wolves gave up a couple of first-quarter touchdowns but then retook the lead in the second (briefly). After a lot of back-and-forth scoring, Aransas State ended up with a loss 56-49 at the finish. QB Trey Owens was 32-of-43 for 418 yards, four scores and two picks in the losing effort.

Southern Miss Golden Eagles Betting Preview

Over on the Southern Miss side, they managed to come out of the gate with a win this year by taking out Alcorn State 49-3. The Eagles have since been on a losing streak over their last four outings, though. Those defeats have come at the hands of Auburn, UConn, Tulane and Troy in succession. That gives Southern Miss a rocky 1-4 record in the books so far.

Matched up against Troy back on October 6, the Eagles gave up 17 unanswered points in the first quarter. As the second quarter wound down Southern Miss was still behind 31-7. The Eagles got a little better from there but still lost 55-34. QB Landry Lyddy was 24-of-37 for 316 yards, two scores and a pick. Robert Briggs carried twice for 44 yards and a touchdown rushing.

Arkansas State Red Wolves @ Southern Miss Golden Eagles Betting Trends: Week 7

Southern Miss Golden Eagles Player Prop Facts

Arkansas State Red Wolves Player Prop Facts

Matchup/League Facts

Arkansas State vs Southern Miss Prediction

I’ll stay with Arkansas State I suppose. Probably not touching this one though. The Red Wolves had a good offensive day (despite the three turnovers) in their loss to South Alabama, notching 31 first downs, 8-of-10 on third-down tries and 418 pass yards. The defense gave up 372 total yards and 296 rush yards though, which put a damper on things. Arkansas State has had some scoring duds this year but they should match up pretty well here.

As for Southern Miss, they gave up 33 first downs, 8-of-14 on third downs and 662 total yards (437 rushing) in their loss to Troy. The Eagles held the ball for just 20:38 of game time, so it’s impressive that they notched 512 yards on offense. Southern Miss will give up another big points total here as well if they’re not careful.

Andrew Jett's Pick: Arkansas State Red Wolves -7

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