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Virginia Tech vs Louisville Prediction 1/24/2026 Today’s College Basketball Picks

Jan 21, 2026; Syracuse, New York, USA; Virginia Tech Hokies forward Tobi Lawal (1) shoots against the Syracuse Orange during the first half at the JMA Wireless Dome. Mandatory Credit: Rich Barnes-Imagn Images

Jan 21, 2026; Syracuse, New York, USA; Virginia Tech Hokies forward Tobi Lawal (1) shoots against the Syracuse Orange during the first half at the JMA Wireless Dome. Mandatory Credit: Rich Barnes-Imagn Images

MATCHUP Virginia Tech Hokies Louisville Cardinals
Team Records 15-5 13-5
Spread +13.5 -112 -13.5 -108
Moneyline +700 -1100
Total Over 160.5 (-112) Under 160.5 (-108)
Where KFC Yum! Center, Louisville, KY
When Saturday, January 24, 2026
Time 02:15 PM EST
TV The CW Network
The Virginia Tech Hokies and the Louisville Cardinals meet Saturday in college basketball action from the KFC Yum! Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Virginia Tech Hokies vs. Louisville Cardinals prediction.

Virginia Tech Hokies Recap

The Virginia Tech Hokies come into this game looking to add on to their 76-74 win over Syracuse last time out to sit at 15-5 this season. After this game, Virginia Tech will head home for a game against Georgia Tech.

Hokies Win Back-To-Back Games

Amani Hansberry leads Virginia Tech in scoring and rebounding with 16.3 PPG and 8.4 RPG along with 3.3 APG while Neoklis Avdalas has 14.6 PPG with 3.5 RPG and a team-high 5 APG to lead the Hokies in assists up to this point in the year. Tobi Lawal has 12.8 PPG and Jaden Schutt has 10.6 PPG while Ben Hammond’s added 10.1 PPG with 3.5 APG to cap off the group of double-digit scorers for Virginia Tech up to this point in the year. Tyler Johnson has 9.5 PPG with 5.3 RPG and Jailen Bedford has 8.3 PPG with 2.8 RPG as well this season. As a team, Virginia Tech is averaging 83.1 PPG on 47% shooting from the field, 35.9% from the foul line and 70.3% from the foul line this season.

Louisville Cardinals Recap


The Louisville Cardinals come into this game looking to add on top their 100-59 win over Pitt last time out to sit at 13-5 this season. After this game, Louisville will head on the road for a game against Duke.

Cardinals Alternate Wins & Losses In 4 Straight


Ryan Conwell leads the Cardinals in scoring with 19.2 PPG along with 4.6 RPG and 2.3 APG while Mikel Brown Jr. has 16.6 PPG with a team-high 5.1 APG to lead the Cardinals in assists and 3 RPG. Isaac McKneely’s added 11.3 PPG with 3.3 RPG and Sananda Fru has 10.7 PPG with 6.3 RPG to lead the Cardinals in rebounding and to round out the group of double-digit scorers for Louisville so far this season. J’Vonne Hadley has 9.9 PPG with 5 RPG while Adrian Wooley’s added 9.1 PPG with 4.6 RPG and Khani Rooths has 6.4 PPG with 4.4 RPG this season. As a team, Louisville is averaging 91.6 PPG on 47.5% shooting from the field, 36% from three and 76.5% from the foul line this season.

Virginia Tech Hokies @ Louisville Cardinals Betting Trends: January 24, 2026


Why the Louisville Cardinals will win

Why the Virginia Tech Hokies will win

Total Points Facts

Matchup/League Facts

Virginia Tech Hokies vs. Louisville Cardinals Prediction


I’m on the Hokies here. I think Louisville is the better team, but this is a ton of points to give to a capable VA Tech team that can still score and has been competitive in a lot of spots already this year. Give me the Hokies and the points in game that Louisville wins, but Virginia Tech covers.

Chris Ruffolo's Pick: Virginia Tech +12.5

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