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Villanova vs USC Prediction 4/3/25 College Basketball Picks

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USC (17-17) vs Villanova (20-14)

Game Info: Thursday, April 3, 2025 at 9:30 pm (MGM Grand Garden Arena)

The Line: Betting Odds: USC +0.0001 — Over/Under: 0.0001

(Get latest betting odds)

In this article, we will formulate a Villanova vs USC prediction for this College Basketball game on Thursday, April 3, at the MGM Grand Garden Arena in Las Vegas, NV. Let’s take a look at the prediction for this game in the quarterfinals of the CBC Tournament. The winner of this game will meet Cincinnati or UCF in the semifinals.

Villanova Wildcats Betting Preview

The Villanova Wildcats (20-14, 18-16 ATS) finished the regular season with three wins in four games; the only loss came to Georgetown. Villanova went to the Big East tournament as the No. 6 seed and defeated Seton Hall in the first round but was powerless against UConn in the second round. The Wildcats destroyed the Colorado Buffaloes 85-64 in the first round of the CBC.

Villanova is averaging 73.7 PPG (192nd) and is allowing 67.4 PPG (50th). The Wildcats are getting 33.8 RPG (309th) and dishing out 12.6 APG (302nd). Eric Dixon is the team’s top performer with 23.0 PPG, 5.1 RPG, and 2.0 APG. Wooga Poplar has 14.7 PPG, a team-high 6.9 RPG, and a team-high 1.3 APG, while Jordan Longino contributes 11.7 PPG, 2.3 RPG, 2.3 APG, and 1.1 SPG.

USC Trojans Betting Preview

The USC Trojans (17-17, 15-19 ATS) have been playing poorly late in the season, as they lost six of the final seven games. The Trojans entered the Big Ten tournament as the No. 14 seed and made a little upset with a double-overtime win against Rutgers in the first round. USC was competitive in the second round against Purdue, but the Boilermakers won 76-71. USC had no issues with Tulane in the first round of the CBC, securing a comfortable 89-60 victory. 

USC averages 77.2 PPG (93rd) and allows 75.0 PPG (272nd). The Trojans are 395th in rebounds (31.5) and 68th in assists (15.6). Desmond Claude leads the team with 16.0 PPG, 3.6 RPG, and 4.3 APG. Wesley Yates III follows him with 14.1 PPG, 2.9 RPG, and 1.2 SPG, while Chibuzo Agbo chips in 11.8 PPG, 4.5 RPG, and 1.0 SPG.

Why Villanova will beat USC

Why USC will beat Villanova

Total Points Facts

Matchup/League Facts

Villanova vs USC Prediction

Villanova won the lone H2H encounter so far when the Wildcats beat the Trojans 94-79 back in 2013. Villanova is a slightly better team, thanks to its defense, while USC doesn’t care much about defensive duties. I like Over/Under records of these teams this season; Villanova is 20-14, and USC is 24-10. Villanova has hit the Game Total Over in 20 of its last 34 games, while the Wildcats have hit the Team Total Under in 12 of their previous 19 games. Additionally, USC has hit the Game Total Over in 23 of its last 33 games, while the Trojans have hit the Team Total Over in 18 of their previous 25 games. I am going with Over.

Oliver Zivic's Pick: Over 151.5

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