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Vanderbilt vs Memphis Prediction 12/17/2025 Today’s College Basketball Picks

Jan 31, 2024; Memphis, Tennessee, USA; Memphis Tigers cheerleaders preform during a time out during the second half against the Rice Owls at FedExForum. Mandatory Credit: Petre Thomas-Imagn Images

Jan 31, 2024; Memphis, Tennessee, USA; Memphis Tigers cheerleaders preform during a time out during the second half against the Rice Owls at FedExForum. Mandatory Credit: Petre Thomas-Imagn Images

MATCHUP Vanderbilt Commodores Memphis Tigers
Team Records 10-0 4-5
Spread -7.5 -108 +7.5 -112
Moneyline -340 +270
Total Over 159.5 (-110) Under 159.5 (-110)
Where FedExForum, Memphis, TN
When Wednesday, December 17, 2025
Time 07:00 PM EST
TV ESPN2

The Vanderbilt Commodores and the Memphis Tigers meet Wednesday in college basketball action from FedExForum in Memphis. Here’s a Vanderbilt vs Memphis prediction. We will look at this from a betting perspective and determine the best Vanderbilt vs Memphis pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Vanderbilt Commodores Betting Preview

Vanderbilt has been cooking so far this year; they’re yet to record a blemish. The Commodores took out Lipscomb, Central Florida, Eastern Kentucky, AR-Pine Bluff and Texas Southern in their first five outings. The most recent five games were all wins over Western Kentucky, VCU, Saint Mary’s, SMU and Central Arkansas. That gives Vanderbilt a very nice 10-0 overall record so far this year.

In the Central Arkansas matchup on Saturday, the Commodores were up comfortably 47-31 by the break. Vanderbilt was outscored by five in the second but held on for the win 83-72 in the end. Tyler Nickel finished with a team-high 30 points and four boards. Both Tyler Tanner (nine rebounds; seven assists) and Jalen Washington (seven rebounds) notched 12 points apiece in the win as well.

Memphis Tigers Betting Preview

Over on the Memphis side, they beat San Francisco in their opener this year, then hit a losing streak versus Ole Miss, UNLV, Purdue and Wake Forest. The Tigers beat Southern Illinois, New Orleans and Baylor in the next trio of games, but then fell versus Louisville over the weekend. In nine games so far this year, that gives Memphis a 4-5 overall record on the card.

Matched up against Louisville on Saturday, the Tigers were outscored by 20 points in the first half. Memphis hit a 42-36 run the rest of the way and limped to the blowout loss 99-73. Hasan Abdul Hakim put up 18 points with four rebounds while Dug McDaniel added 16 points with two rebounds. Sincere Parker added 12 points with four rebounds and three assists in the losing effort as well.

Vanderbilt Commodores @ Memphis Tigers Betting Trends: December 17, 2025

Why the Memphis Tigers will win

Why the Vanderbilt Commodores will win

Vanderbilt vs Memphis Prediction

I’ll stick with Vanderbilt. The Commodores are chugging along nicely so far on a spotless record. In their latest win versus Central Arkansas over the weekend, Vanderbilt shot 42.2 percent from the field with 13 turnovers but also hit 18-of-22 (81.8 percent) from the line with a 44-31 rebounding advantage. Vanderbilt is scoring great so far this year; they’ve got 83 or more points in all 10 games.

As for Memphis, they struggled against a good Louisville team in their last outing. The Tigers shot 41.2 percent from the field with a 32-30 rebounding deficit but did well in the paint on a 40-24 scoring advantage. Memphis has 68 or more points in every game so far this year themselves, however they’re giving up a lot of scoring to capable offenses on the other side; 70 or more in each of the last three games.

Andrew Jett's Pick: Vanderbilt Commodores -7.5

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