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UConn vs Duke Prediction 3/29/2026 Today’s College Basketball Picks

Mar 27, 2026; Washington, DC, USA; Michigan State Spartans forward Jaxon Kohler (0) grabs a rebound on UConn Huskies forward Tarris Reed Jr. (5) in the second half during a Sweet Sixteen game of the East Regional of the men's 2026 NCAA Tournament at Capital One Arena. Mandatory Credit: Amber Searls-Imagn Images

Mar 27, 2026; Washington, DC, USA; Michigan State Spartans forward Jaxon Kohler (0) grabs a rebound on UConn Huskies forward Tarris Reed Jr. (5) in the second half during a Sweet Sixteen game of the East Regional of the men's 2026 NCAA Tournament at Capital One Arena. Mandatory Credit: Amber Searls-Imagn Images

MATCHUP UConn Huskies Duke Blue Devils
Team Records 32-5 35-2
Spread +5.5 -118 -5.5 -102
Moneyline +180 -218
Total Over 133.5 (-115) Under 133.5 (-105)
Where Duke Stadium
When Sunday, March 29, 2026
Time 05:05 PM EDT
TV CBS
In this article we will formulate a UConn vs Duke prediction for this College Basketball game on Sunday, March 29th at Capital One Arena in Washington, DC. Let’s take a look at the prediction for this NCAA Tournament matchup.

UConn Huskies Betting Preview

The UConn Huskies are 32-5 (17-3) this season after they defeated Michigan State by a score of 67-63 in their last game. UConn led 35-27 at halftime, but they were outscored 36-32 in the second half in the win. The Huskies shot 46% from the field, 43% on three pointers, and 63% on free throws in the game. Tarris Reed Jr led UConn with 20 points and five rebounds, while Alex Karaban added 17 points and seven rebounds in the win. 

Prior to that game, UConn defeated UCLA by a score of 73-57 and Furman by a score of 82-71. The Huskies have scored 77.2 points per game with 36.6 rebounds and 18.5 assists per game, while they have allowed 65.0 points against per game this season. Tarris Reed Jr is averaging 14.3 points and 8.8 rebounds per game, while Alex Karaban is averaging 13.4 points and 5.2 rebounds per game for the Huskies. UConn is shooting 48.2% from the field, 71.6% on free throws, and 35.2% on three pointers this season. 

Duke Blue Devils Betting Preview

The Duke Blue Devils are 35-2 (17-1) this year after they defeated St. John’s by a score of 80-75 in their last game. Duke trailed 40-39 at halftime, but they won the second half 41-35 for the victory. The Blue Devils shot 54% from the field, 36% on three pointers, and 63% on free throws in the game. Isaiah Evans led Duke with 25 points and four rebounds, while Cameron Boozer added 22 points and 10 rebounds in the win. 

Prior to that game, Duke defeated TCU by a score of 81-58 and Siena by a score of 71-65, but they did trail in the second half of both games. The Blue Devils have scored 81.9 points per game with 40.4 rebounds and 16.7 assists per game, while they have allowed 63.4 points against per game this season. Cameron Boozer is averaging 22.4 points and 10.3 rebounds per game, while Isaiah Evans is averaging 15.2 points and 3.3 rebounds per game for the Blue Devils. Duke is shooting 49.0% from the field, 72.4% on free throws, and 35.1% on three pointers this year.

Why the Duke Blue Devils will win

Why the Connecticut Huskies will win

Total Points Facts

Matchup/League Facts

UConn vs Duke Prediction 

Duke came into this tournament as the #1 overall seed, but they have had plenty of issues in their first three games, as they have trailed in the second half of all three games. The Blue Devils are shooting 49% from the field and they have allowed 65 points or fewer in three of their last five games. UConn nearly blew a huge lead against MSU in their last game and they are also very strong defensively, as they have allowed 63 points or fewer in three of their last five. Duke definitely has a few flaws that teams have targeted, but I think they matchup with UConn very well. Take the Blue Devils here.

David Racey's Pick: Duke -5.5

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