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Syracuse vs Louisville Prediction 3/3/2026 Today’s College Basketball Picks

Louisville Cardinals center Aly Khalifa (15) is defended by Clemson Tigers forward Nick Davidson (11) Saturday, Feb. 28, 2026, during the NCAA men’s basketball game at Littlejohn Coliseum in Clemson, South Carolina. Clemson Tigers won 80-75.

Louisville Cardinals center Aly Khalifa (15) is defended by Clemson Tigers forward Nick Davidson (11) Saturday, Feb. 28, 2026, during the NCAA men’s basketball game at Littlejohn Coliseum in Clemson, South Carolina. Clemson Tigers won 80-75.

MATCHUP Syracuse Orange Louisville Cardinals
Team Records 15-14 20-9
Spread +12.5 -108 -12.5 -112
Moneyline +650 -1000
Total Over 158.5 (-112) Under 158.5 (-108)
Where KFC Yum! Center, Louisville, KY
When Tuesday, March 3, 2026
Time 09:00 PM EST
TV ACC Network
In this article, we will formulate a Syracuse vs Louisville Prediction for this college basketball game on Tuesday, March 3rd. Let’s take a look at the prediction for this college basketball matchup.

Louisville Cardinals Preview


The Louisville Cardinals have a 20-9 overall record and a 9-7 record in the ACC. They are coming off an 80-75 road loss against Clemson and their previous three games were a 77-74 road loss against North Carolina, an 87-70 home win against Georgia Tech and a 95-85 road loss against SMU.

Offensively, Louisville averages 86 points per game, while allowing 72.2 points per game defensively. The Cardinals shoot with 47% from the field and grab 39.4 rebounds per game, while dishing out 17.3 assists per game. They average 3.3 blocks per game and 7.1 steals per game defensively.

Ryan Conwell leads Louisville in scoring, with an average of 18.4 points per game, while shooting with 40.5% from the field and 84.2% from the free throw line. Sananda Fru is the team’s leading rebounder with 6.4 per game. Aly Khalifa leads the team in assists with 2.7 per game.

Syracuse Orange Preview


The Syracuse Orange have a 15-14 overall record and a 6-10 record in the ACC. They are coming off an 88-83 road loss against Wake Forest and their previous three games were a 77-64 home loss against North Carolina, a 101-64 road loss against Duke and a 79-78 home win against SMU.

Offensively, Syracuse averages 75.9 points per game, while allowing 73.9 points per game defensively. The Orange shoot with 47% from the field and grab 34.2 rebounds per game, while dishing out 13 assists per game. They average 6 blocks per game and 6.4 steals per game defensively.

J.J. Starling leads Syracuse in scoring, with an average of 12 points per game, while shooting with 43.8% from the field and 54.8% from the free throw line. William Kyle III is the team’s leading rebounder with 7.3 per game. Naithan George leads the team in assists with 5.4 per game.

Syracuse Orange @ Louisville Cardinals Betting Trends: March 3, 2026


Why the Louisville Cardinals will win

Why the Syracuse Orange will win

Total Points Facts

Syracuse vs Louisville Prediction


In this Syracuse vs Louisville Prediction, Louisville is coming as -15.5 home favorites. Louisville has been the better team this season but has been struggling lately with a 1-3 record in its last 4 games and has failed to cover the spread in its last 4 games. Syracuse has lost and failed to cover its last three games and have been terrible on the road, while having an inferior offense, scoring 10.1 points per game less than the hosts. I like Louisville to take care of business and cover the spread at home in this one.

Nikos Lagouretos's Pick: Louisville -15.5

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