St. Louis vs Duquesne Prediction 1/20/2026 Today’s College Basketball Picks

The Saint Louis Billikens and the Duquesne Dukes meet Tuesday in college basketball action from the UPMC Cooper Fieldhouse. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Saint Louis Billikens vs. Duquesne Dukes prediction.

Saint Louis Billikens Recap

The Saint Louis Billikens come into this game looking to add on to their 88-63 win over Richmond last time out to sit at 17-1 this season. After this game, Saint Louis will head on the road for a game against St. Bonaventure.

Billikens Win 11 Straight

Robbie Avila leads the Billikens in scoring with 12.8 PPG along with a team-high 3.8 APG and 4.3 RPG while Dion Brown has 11.5 PPG with a team-high 6.1 RPG to lead the Billikens in rebounding. Amari McCottry has 10.9 PPG with 5.6 RPG and 2.9 APG. Trey Green has 10.8 PPG with 2.9 RPG and Kellen Thames has 10.6 PPG with 5.8 RPG along with 2.2 APG. Quentin Jones has 10.4 PPG with 3.9 RPG and 2.9 APG to cap off the scoring in double figures for the Billikens this season. As a team, Saint Louis is averaging 91.7 PPG on 51.9% shooting from the field, 38.2% from three and 76.8% from the foul line this season.

Duquesne Dukes Recap

The Duquesne Dukes come into this game looking to add on to their 74-63 win over Fordham last time out to sit at 10-8 this season. After this game, Duquesne will head on the road for a game against Loyola Chicago.

Dukes Snap Three-Game Skid

Tarence Guinyard leads the Dukes in scoring and assists with 16.2 PPG and 5.4 APG along with 3.3 RPG while John Hugley IV has 13.7 PPG with 5.3 RPG and 2 APG. Jimmie Williams has 15.3 PPG with 4.3 RPG and 2.5 APG to cap off the trio of double-digit scorers for Duquesne up to this point in the year. Maximus Edwards has 7.4 PPG with 3.1 RPG and Jakub Necas also has 8.4 PPG with a team-high 5.7 RPG to lead the Dukes in rebounding as well this season. As a team, Duquesne is averaging 84.4 PPG on 49% shooting from the field, 35.3% from three and 70.8% from the foul line this season.

Saint Louis Billikens @ Duquesne Dukes Betting Trends: January 20, 2026

Why the Duquesne Dukes will win

• Saint Louis has lost each of its last six night games at UPMC Cooper Fieldhouse.
• Duquesne has won six of its last seven home games against Saint Louis at UPMC Cooper Fieldhouse.
• Duquesne has won the first half in each of its last seven night games against Saint Louis.

Why the Saint Louis Billikens will win

• Saint Louis has won each of its last 11 games.
• Duquesne has lost six of its last seven night games against AP-ranked opponents.
• Saint Louis has won the first half in each of its last 12 games.

Total Points Facts

• Thirty-five of Duquesne’s last 37 night games against Conference opponents at UPMC Cooper Fieldhouse have produced a total of 165 or fewer points.
• Fifteen of Saint Louis’ last 16 night games against Conference opponents have produced a total of 156 or fewer points.

Matchup/League Facts

• Duquesne ranks 31st among Division 1 teams for effective field goal percentage this season (56.8%).
• Duquesne ranks 34th among Division 1 teams for field goal percentage this season (49.0%).
• Saint Louis ranks 1st among Division 1 teams for point differential per game this season (+25.2).
• Saint Louis ranks 1st among Division 1 teams for opponent field goal percentage this season (35.6%).

Saint Louis Billikens vs. Duquesne Dukes Prediction

I’m on Saint Louis in this one. I get the case to be made for the Dukes, but Saint Louis is the far better team here and continues to be one of the best teams in the A-10 this season regardless of where this team is playing their games. Duquesne has been decent in spots, but mostly against the bad teams they’ve gone up against and I think this game is a struggle spot for the Dukes. Give me Duquesne.

Chris Ruffolo's Pick: Saint Louis -9.5