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St. John’s vs Iowa State Prediction 11/24/2025 Today’s College Basketball Picks

Iowa State Cyclones guard Tamin Lipsey (3) reacts after making a three-point shot against Stonehill during the second half in the NCAA basketball on Nov. 17, 2025, at Hilton Coliseum in Ames, Iowa.Iowa.

Iowa State Cyclones guard Tamin Lipsey (3) reacts after making a three-point shot against Stonehill during the second half in the NCAA basketball on Nov. 17, 2025, at Hilton Coliseum in Ames, Iowa.Iowa.

MATCHUP St. John's Red Storm Iowa State Cyclones
Team Records 3-1 4-0
Spread +2.5 -110 -2.5 -110
Moneyline +114 -135
Total Over 161.5 (-108) Under 161.5 (-112)
Where Michelob ULTRA Arena, Las Vegas, NV
When Monday, November 24, 2025
Time 04:30 PM EST
TV truTV

The St. John’s Red Storm and the Iowa State Cyclones meet Monday in college basketball action from the Michelob ULTRA Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a St. John’s Red Storm vs. Iowa State Cyclones prediction.

St. John’s Red Storm Recap

The St. John’s Red Storm come into this game looking to add on to their 3-1 start to the year after a 97-49 win over Bucknell last time out. After this game, St. John’s will square off against Baylor.

Red Storm Win Back-To-Back Games

Bryce Hopkins leads St. John’s in scoring with 15.5 PPG along with 3.8 RPG and 2.8 APG while Zuby Ejiofor has 15 PPG with 6.3 RPG and 3 APG as well this season. Ian Jackson has 14.5 PPG with 3 RPG and Joson Sanon has 11.5 PPG with 3.8 RPG. Dillon Mitchell has 10.8 PPG with a team-high 6.5 RPG to lead the Red Storm in rebounding while Oziyah Sellers has 8.8 PPG with 4 RPG and Dylan Darling has 7 PPG with 4 RPG and a team-high 4.7 APG to lead the Red Storm in assists. As a team, St. John’s is averaging 98.5 PPG on 51.1% shooting from the field, 33.3% from three and 69.4% from the foul line this season.

Iowa State Cyclones Recap

The Iowa State Cyclones come into this game looking to add on to their 96-57 win over Stonehill last time out to sit at 4-0 this season. After this game, Iowa State will duke it out against Creighton.

Cyclones Looking To Stay Unbeaten

Tamin Lipsey leads the Cyclones in scoring and assists with 19 PPG and 5.3 APG along with 4.3 RPG and 3.8 SPG while Joshua Jefferson has 18.8 PPG with a team-high 7.8 RPG to lead Iowa State in rebounding and 4.3 APG as well this season. Milan Momcilovic has 15.3 PPG has 2.8 RPG to cap off the trio of double-digit scorers for Iowa State so far this season. Killyan Toure has 9.3 PPG with 2.3 SPG and Dominick Nelson has 8 PPG and Blake Buchana has 7.8 PPG with 5.5 RPG as well this season. As a team, Iowa State is averaging 95.5 PPG on 54.2% shooting from the field, 35.6% from three and 66.7% from the foul line this season. 

St. John’s Red Storm @ Iowa State Cyclones Betting Trends: November 24, 2025


Why the Iowa State Cyclones will win

Why the St. John’s Red Storm will win

Total Points Facts

Matchup/League Facts

St. John’s Red Storm vs. Iowa State Cyclones Prediction

I’m on Iowa State here. I get the case to be made for St. John’s as the Red Storm have a potent team that can make a tournament run in March. However, Iowa State is no joke either and they slapped around Mississippi State in their lone step up game so far this season. We’ve also seen the Cyclones post the perfect balance of offense and defense under Otzelberger. I’ll roll with Iowa State here.

Chris Ruffolo's Pick: Iowa State -2.5

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