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Southern Illinois vs Memphis Prediction 11/26/2025 Today’s College Basketball Picks

Memphis Tiger Dug McDaniel (1) calls out a play against UNLV during a basketball game on Nov. 16, 2025 at the FedExForum in Memphis, Tennessee.

Memphis Tiger Dug McDaniel (1) calls out a play against UNLV during a basketball game on Nov. 16, 2025 at the FedExForum in Memphis, Tennessee.

MATCHUP Southern Illinois Salukis Memphis Tigers
Team Records 3-3 1-4
Spread +10.5 -108 -10.5 -112
Moneyline +470 -650
Total Over 159.5 (-110) Under 159.5 (-110)
Where FedExForum, Memphis, TN
When Wednesday, November 26, 2025
Time 08:00 PM EST
TV ESPN+

In this article we will formulate a Southern Illinois vs Memphis prediction for this College Basketball game on Wednesday, November 26th at the FedEx Forum in Memphis, Tennessee. Let’s take a look at the prediction for this College Basketball matchup.

Southern Illinois Salukis Betting Preview

The Southern Illinois Salukis are 3-3 this season after they lost to UAB by a score of 81-73 in their last game. Southern Illinois trailed 36-35 at halftime and allowed 45 points in the second half for the loss. The Salukis shot 43% from the field, 17% on three pointers, and 85% on free throws in the game. Quel’Ron House led Southern Illinois with 18 points and one assist, while Prince Aligbe added 13 points and seven rebounds in the loss. 

Prior to that game, Southern Illinois defeated Delaware by a score of 79-59, but lost to North Dakota State by a score of 92-85 before that. The Salukis have scored 83.7 points per game with 41.3 rebounds and 15.8 assists per game, while they have allowed 73.0 points against per game this season. Quel’Ron House is averaging 18.2 points and 2.8 assists per game, while Davion Sykes is averaging 10.7 points and 5.3 rebounds per game for the Salukis. Southern Illinois is shooting 50.4% from the field, 69.2% on free throws, and 24.1% on three pointers this season. 

Memphis Tigers Betting Preview

The Memphis Tigers are 1-4 this year after they lost to Wake Forest by a score of 69-68 in their last game. Memphis led 33-27 at halftime, but was outscored 42-35 in the second half for the loss. The Tigers shot 41% from the field, 38% on three pointers, and 61% on free throws in the game. Dug McDaniel led Memphis with 24 points and six assists, while Zach Davis added 12 points and five rebounds in the loss. 

Prior to that game, Memphis lost to Purdue by a score of 80-71 and UNLV by a score of 92-78. The Tigers have scored 74.0 points per game with 35.4 rebounds and 14.2 assists per game, while they have allowed 78.8 points against per game this season. Dug McDaniel is averaging 14.8 points and 5.8 assists per game, while Ashton Hardaway is averaging 8.8 points and 2.0 rebounds per game for the Tigers. Memphis is shooting 42.3% from the field, 67.2% on free throws, and 31.9% on three pointers this year. 

Why the Memphis Tigers will win

Why the Southern Illinois Salukis will win

Total Points Facts

Southern Illinois vs Memphis Prediction 

Memphis comes into this matchup on a four game losing streak and they played very poorly in the second half against Wake Forest in their last game. The Tigers are shooting 42% from the field this year and they have allowed at least 80 points in three of their last four. SIU has lost three of their last four games and while they are shooting 50% from the field, they have allowed 81+ points in those three losses. I think we could see a higher scoring game here, but I like Memphis to get back on track with a blowout win.

David Racey's Pick: Memphis -10.5

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