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South Dakota vs Creighton Prediction 11/5/2025 Today’s College Basketball Picks

Mar 23, 2014; San Antonio, TX, USA; Creighton Bluejays forward Doug McDermott (3) shoots against the Baylor Bears in the second half of a men's college basketball game during the third round of the 2014 NCAA Tournament at AT&T Center. Mandatory Credit: Kevin Jairaj-Imagn Images

Mar 23, 2014; San Antonio, TX, USA; Creighton Bluejays forward Doug McDermott (3) shoots against the Baylor Bears in the second half of a men's college basketball game during the third round of the 2014 NCAA Tournament at AT&T Center. Mandatory Credit: Kevin Jairaj-Imagn Images

South Dakota (0-1) vs Creighton (0-0)

November 5, 2025 at 08:00 PM EST

The Line: Betting Odds: Creighton -28 — Over/Under: TBA

(Get latest betting odds)

In this article, we will formulate a South Dakota vs Creighton Prediction for this College Basketball game on Wednesday, November 5th. Let’s take a look at the prediction for this College Basketball matchup.

Creighton Bluejays Preview

The Creighton Bluejays finished last season a 25-11 record and were placed 2nd in the Big East with a 15-5 conference record. The Bluejays were 20-14-2 against the spread, and 18-18-0 in over/under, having a 15-2 home record and a 6-5 away record.

Offensively last season, Creighton scored 75.5 points per game, which ranked 133rd in the nation, while defensively, they allowed 70.0 points per game (112th). The Bluejays shot with 47.7% from the field (35th), and with 34.5% from beyond the arc (157th). They shot with 72.8% from the free throw line (153rd), and grabbed 37.4 rebounds per game (324th), while dishing out 17.1 assists per game (16th) and committing 12.2 turnovers per game (235th).

Ryan Kalkbrenner led Creighton in scoring last season, with an average of 19.2 points, 8.7 rebounds and 1.5 assists. Steven Ashworth followed with 16.4 points, 4.1 rebounds and 6.8 assists per game, while Pop Isaacs added 16.3 points, 4.8 rebounds and 3.9 assists per game.

South Dakota Coyotes Preview

The South Dakota Coyotes finished last season a 19-14 record and were placed 5th in the Summit with a 9-7 conference record. The Coyotes were 17-12-1 against the spread, and 21-8-1 in over/under, having a 14-2 home record and a 4-11 away record.

Offensively last season, South Dakota scored 85.2 points per game, which ranked 3rd in the nation, while defensively, they allowed 83.7 points per game (362nd). The Coyotes shot with 45.0% from the field (160th), and with 32.1% from beyond the arc (290th). They shot with 71.4% from the free throw line (221st), and grabbed 35.7 rebounds per game (73rd), while dishing out 11.6 assists per game (319th) and committing 9.6 turnovers per game (17th).

Chase Forte led South Dakota in scoring last season, with an average of 17.9 points, 4.4 rebounds and 3.2 assists. Isaac Bruns followed with 14.6 points, 4.3 rebounds and 0.6 assists per game, while Quandre Bullock added 12.1 points, 3.6 rebounds and 1.6 assists per game.

South Dakota Coyotes @ Creighton Bluejays Betting Trends: November 5, 2025


Why the Creighton Bluejays will win

  • Creighton has won 12 of its last 13 games against non-Conference opponents at CHI Health Center Omaha.
  • South Dakota has lost 10 of its last 11 road games against non-Conference opponents.
  • Creighton has won the first half in each of its last 12 games against the Summit League.

Why the South Dakota Coyotes will win

  • South Dakota has won each of its last three games following a home loss.
  • Creighton has lost three of its last four night games against non-Conference opponents.

South Dakota vs Creighton Prediction

In this South Dakota vs Creighton Prediction, Creighton is coming as -28.5 home favorites. Creighton is coming off an excellent season with a 25-11 record and were dominating at home, having lost just twice in their 17 home games. They are up against a South Dakota team that struggled on the road and had the third-worst defense in the whole country, allowing 83.7 points per game. I expect the host to get the job done in their season opener in front of their home crowd, so take Creighton and lay the points in this one.

Nikos Lagouretos's Pick: Creighton -28

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