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Santa Clara vs St. Louis Prediction 11/27/2025 Today’s College Basketball Picks

St. Thomas More High School's Amari McCottry (4) and Sekou Konneh (25) embrace during a timeout against Lakeside Lutheran High School in the Division 3 state championship game during the WIAA state boys basketball tournament on Saturday, March 16, 2024 at the Kohl Center in Madison, Wis. St. Thomas More won the game, 65-54.
Tork Mason/USA TODAY NETWORK-Wisconsin

St. Thomas More High School's Amari McCottry (4) and Sekou Konneh (25) embrace during a timeout against Lakeside Lutheran High School in the Division 3 state championship game during the WIAA state boys basketball tournament on Saturday, March 16, 2024 at the Kohl Center in Madison, Wis. St. Thomas More won the game, 65-54. Tork Mason/USA TODAY NETWORK-Wisconsin

MATCHUP Santa Clara Broncos St. Louis Billikens
Team Records 6-0 5-0
Spread +1.5 -105 -1.5 -115
Moneyline +110 -130
Total Over 159.5 (-110) Under 159.5 (-110)
Where Acrisure Arena, Palm Springs, CA
When Thursday, November 27, 2025
Time 07:00 PM EST
TV CBSSN
The Santa Clara Broncos and Saint Louis Billikens meet Thursday in the college basketball action at the Acrisure Arena. Here’s a Santa Clara vs St. Louis Prediction. This article will include a Santa Clara vs St. Louis Pick.

Santa Clara Broncos Betting Preview


The Santa Clara Broncos beat Louisiana and Idaho State, and they play Utah Tech next. Santa Clara has won 13 of its last 17 games.

The Santa Clara Broncos are averaging 81.8 points on 46.4 percent shooting and allowing 61.5 points on 36.9 percent shooting. Christian Hammond is averaging 17 points and 4.3 rebounds, while Elijah Mahi is averaging 12.5 points and 3.8 rebounds. Bukky Oboye is the third double-digit scorer and Allen Graves is grabbing 7.3 rebounds. The Santa Clara Broncos are shooting 30.9 percent from beyond the arc and 63.5 percent from the free throw line. The Santa Clara Broncos are allowing 27.8 percent shooting from deep and are grabbing 38.8 rebounds per game.

Saint Louis Billikens Betting Preview


The Saint Louis Billikens beat Grand Canyon and Fort Wayne, and they play Loyola Marymount next. Saint Louis has won 7 of its last 9 games.

The Saint Louis Billikens are averaging 95.6 points on 52.9 percent shooting and allowing 69.7 points on 36 percent shooting. Amari McCottry is averaging 14.8 points and 6.4 rebounds, while Robbie Avila is averaging 13.6 points and 2.6 assists. Dion Brown is the third double-digit scorer and Ishan Sharma is grabbing 2.4 rebounds. The Saint Louis Billikens are shooting 39.3 percent from beyond the arc and 83.2 percent from the free throw line. The Saint Louis Billikens are allowing 24.8 percent shooting from deep and are grabbing 52.3 rebounds per game.

Why the Saint Louis Billikens will win

Why the Santa Clara Broncos will win

Total Points Facts

Santa Clara vs St. Louis Prediction


You can make a case for either of these unbeaten teams that are rolling on both sides of the ball and are a combined 8-2 ATS. However, I’m rolling with Saint Louis. I was high on the Billikens last season and while things didn’t quite work out, there’s a chance for a bounce back season. Avila is a superstar big man and Brown is a proven scorer with playmaking ability. The line is more than reasonable. I’ll side with Saint Louis, a team that should make a run in the A10.

Randy Chambers's Pick: St. Louis -1.5

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