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San Francisco vs St. Louis Prediction 12/13/2025 Today’s College Basketball Picks

Jeremy Dent-Smith, 25, of Stanford shoots over Robbie Avila, 21, of St. Louis University in the Acrisure Invitational Champioship game at Acrisure Arena in Palm Desert, Calif., Nov. 28, 2025.

Jeremy Dent-Smith, 25, of Stanford shoots over Robbie Avila, 21, of St. Louis University in the Acrisure Invitational Champioship game at Acrisure Arena in Palm Desert, Calif., Nov. 28, 2025.

MATCHUP San Francisco Dons St. Louis Billikens
Team Records 6-4 8-1
Spread +11.5 -112 -11.5 -108
Moneyline +525 -750
Total Over 154.5 (-115) Under 154.5 (-105)
Where Chaifetz Arena, St. Louis, MO
When Saturday, December 13, 2025
Time 08:00 PM EST
TV ESPN+
The San Francisco Dons and Saint Louis Billikens meet Saturday in the college basketball action at the Chaifetz Arena. Here’s a San Francisco vs St. Louis Prediction. This article will include a San Francisco vs St. Louis Pick.

San Francisco Dons Betting Preview


The San Francisco Dons beat Miss State, lost to North Alabama, and they play Loyola Chicago next. San Francisco has lost 3 of its last 4 games.

The San Francisco Dons are averaging 74.6 points on 45.3 percent shooting and allowing 67.9 points on 40.4 percent shooting. Ryan Beasley is averaging 13 points and 2.9 rebounds, while Mookie Cook is averaging 11.7 points and 6 rebounds. Tyrone Riley IV is the third double-digit scorer and David Fuchs is dishing 1.1 assists. The San Francisco Dons are shooting 36.5 percent from beyond the arc and 70.6 percent from the free throw line. The San Francisco Dons are allowing 32.9 percent shooting from deep and are grabbing 34.7 rebounds per game.

Saint Louis Billikens Betting Preview


The Saint Louis Billikens beat Loyola Marymount and Central Michigan, and they play Bethune-Cookman next. Saint Louis has won 8 of its last 9 games.

The Saint Louis Billikens are averaging 89.8 points on 49.7 percent shooting and allowing 70.3 points on 36.9 percent shooting. Robbie Avila is averaging 12.4 points and 4.8 rebounds, while Dion Brown is averaging 12.4 points and 2 assists. Trey Green is the third double-digit scorer and Amari McCottry is grabbing 5.3 rebounds. The Saint Louis Billikens are shooting 35.2 percent from beyond the arc and 82.3 percent from the free throw line. The Saint Louis Billikens are allowing 27.6 percent shooting from deep and are grabbing 40.9 rebounds per game.

Why the Saint Louis Billikens will win

Why the San Francisco Dons will win

Total Points Facts

Matchup/League Facts

San Francisco vs St. Louis Prediction


San Francisco usually has a decent basketball team, but those recent losses to Nevada and North Alabama are a serious turn-off. San Francisco has these moments where it just can’t buy a basket. I was high on Saint Louis last season, but it looks like this year’s version is the team to have expectations. Saint Louis is rolling on both sides of the ball and looks deep offensively. Saint Louis should make some noise in the A10 and make a push for a potential berth in the big dance. The Billikens should have a field day in this spot. I’ll lay the points.

Randy Chambers's Pick: St. Louis -11.5

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