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Pennsylvania vs Yale Prediction 2/21/2026 Today’s College Basketball Picks

Dec 29, 2025; Tuscaloosa, Alabama, USA; Yale Bulldogs forward Nick Townsend (42) dribbles against Alabama Crimson Tide center Noah Williamson (15) during the second half at Coleman Coliseum. Mandatory Credit: David Leong-Imagn Images

Dec 29, 2025; Tuscaloosa, Alabama, USA; Yale Bulldogs forward Nick Townsend (42) dribbles against Alabama Crimson Tide center Noah Williamson (15) during the second half at Coleman Coliseum. Mandatory Credit: David Leong-Imagn Images

MATCHUP Pennsylvania Quakers Yale Bulldogs
Team Records 13-11 21-4
Where John J. Lee Amphitheater, New Haven, CT
When Saturday, February 21, 2026
Time 02:00 PM EST
TV ESPN+
The Penn Quakers and Yale Bulldogs meet Saturday in college basketball action at the John J. Lee Amphitheater. Here’s a Pennsylvania vs. Yale prediction. This article will include a Pennsylvania vs. Yale pick.

Penn Quakers Betting Preview


The Penn Quakers beat Columbia and Cornell, and they play Dartmouth next. Penn has won 4 straight games.

The Penn Quakers are averaging 80.1 points on 44.4 percent shooting and allowing 78 points on 45.6 percent shooting. Ethan Roberts is averaging 17.4 points and 2.4 assists, while TJ Power is averaging 15 points and 7.2 rebounds. Michael Zanoni is the third double-digit scorer, and AJ Levine is dishing out 4.1 assists. The Penn Quakers are shooting 37.7 percent from beyond the arc and 69.2 percent from the free throw line. The Penn Quakers are allowing 32.5 percent shooting from deep and are grabbing 34.2 rebounds per game.

Yale Bulldogs Betting Preview


The Yale Bulldogs beat Dartmouth and Harvard, and they play Cornell next. Yale has won 8 of its last 9 games.

The Yale Bulldogs are averaging 83.3 points on 50 percent shooting and allowing 71.5 points on 43.7 percent shooting. Nick Townsend is averaging 16.5 points and 7.6 rebounds, while Isaac Celiscar is averaging 12.3 points and 5.4 rebounds. Riley Fox is the third double-digit scorer, and Trevor Mullin is grabbing 2.3 rebounds. The Yale Bulldogs are shooting 41.9 percent from beyond the arc and 76.5 percent from the free throw line. The Yale Bulldogs are allowing 34.5 percent shooting from deep and are grabbing 32.4 rebounds per game.

Why the Yale Bulldogs will win

Why the Penn Quakers will win

Total Points Facts

Pennsylvania vs Yale Prediction


Yale is the better team and has won 9 of the last 10 games against Penn. We saw the Quakers lose by 17 points to Yale last month. However, Yale hasn’t been covering these big numbers lately and is 1-5 ATS in its last 6 games overall. We’ve also seen Yale outright lose to Harvard and Princeton as big favorites over its last 10 games. Penn has quietly won 4 straight games, which includes upsets over Cornell twice. This line feels a bit inflated, and I’m not buying it. Give me Penn and the points on Saturday.

Randy Chambers's Pick: Penn +10.5

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